| 摘要: |
| 目的：应用超声技术评价缺血性二尖瓣反流（Ischemic Mitral Regurgitation, IMR）患者冠脉介入治疗术前、术后左室收缩功能及二尖瓣反流容积变化，探索IMR发生机制，预测IMR发展，从而为临床治疗提供帮助。方法：运用超声技术分析41例患者冠脉介入治疗术前及术后左室应变，并评估二尖瓣反流容积。根据二尖瓣反流变化情况将患者分为非恶化组（Ⅰ组）和恶化组（Ⅱ组）。结果：I组：患者术后纵向和径向应变均较术前改善，其中，术后径向应变及左室射血分数与术前相比显著提高（P＜0.05）；Ⅱ组：患者术后左室射血分数较术前提高无统计学意义（P＞0.05），左室舒张末期内径有增大趋势。结论：超声技术可以较敏感的评价左室心肌功能。冠状动脉介入治疗通过改善左室收缩功能可以减少IMR。 |
| 关键词: 缺血性二尖瓣反流 斑点追踪 心肌应变 |
| DOI： |
| 投稿时间：2016-03-28修订日期：2016-04-18 |
| 基金项目:多巴酚丁胺负荷试验结合实时三维超声心动图评价缺血性二尖瓣反流的研究 |
|
| Echocardiography comparison of Ischemic mitral regurgitation before and after percutaneous coronary intervention |
|
| () |
| Abstract: |
| Objectives：The purpose of the study is to assess the variation of left ventricular function and ischemic mitral regurgitation volume before and after percutaneous coronary intervention (PCI) by echocardiography. Thus we can improve the understanding of IMR and help clinical decision make. Methods：We evaluated the left ventricular function and IMR before and after PCI by echocardiography. Then divided the patients into two groups by the variation of mitral regurgitation volume (group one: IMR volume diminish or increase less than 15 ml; group two: IMR volume increase more than or equal to 15ml). Results：Postoperative left ventricular radial strain and ejection fraction has significant improvement in group one. And postoperative left ventricular longitudinal strain has improved compared to preoperative status. In group two, postoperative left ventricular ejection fraction has no significant improvement, whereas left ventricular end-diastolic diameter has enlarged. Conclusions：Echocardiography can evaluate left ventricular muscle function sensitively. PCI can help reduce IMR by improving left ventricular systolic function. |
| Key words: Ischemic mitral regurgitation, Speckle tracking, Myocardial strain |
