| 摘要: |
| 目的：观察阻塞性睡眠呼吸暂停综合症患者右心室心肌应变特点,探讨QLAB和速度向量成像技术(VVI)评价阻塞性睡眠呼吸暂停综合症患者右心室收缩功能的价值及其临床意义。方法：选取阻塞性睡眠呼吸暂停综合症患者45名,于心尖四腔心切面,分别用QLAB软件和VVI软件获取右心室各节段心肌应变曲线,记录右心室整体纵向收缩期应变(GLSRV-QLAB 、GLSRV-VVI)。结果：GLSRV-QLAB 和GLSRV-VVI与传统超声心动图右心室收缩功能参数表现出显著相关性。 GLSRV-QLAB和RVFAC有显著相关性(r = -0.832,P <0.001),和TAPSE有显著相关性(r = -0.868,P <0.001),GLSRV-VVI和RVFAC有显著相关性(r=-0.716,P <0.001),和TAPSE有显著相关性(r = -0.804,P <0.001)。GLSRV-QLAB和GLSRV-VVI有显著相关性(r = 0.833,P <0.001)。以RVFAC<35％判定右心室收缩功能减低,GLSRV-QLAB预测右心室功能障碍的最佳截点值为-19.852％(95％CI：0.735 -0.951)(AUC = 0.869,P <0.001),灵敏度80.0％,特异性86.7％。GLSRV-VVI预测右心室收缩功能障碍的最佳截点值为-19.99％(95％CI：0.711 - 0.938)(AUC = 0.849,P <0.001),灵敏度73.3%,特异性86.7％。通过Hanley-McNeil法比较GLSRV-QLAB 和GLSRV-VVI的曲线下面积无显著差异(差异= 0.020,95％CI：-0.0791-0.119,P =0.693)。结论：GLSRV-VVI技术和GLSRV-QLAB可以准确评价阻塞性睡眠呼吸暂停综合症患者右心室功能,为临床评价右心室功能提供较好的检测方法。 |
| 关键词: 二维斑点追踪成像 阻塞性睡眠呼吸暂停综合症 右心室功能 应变 |
| DOI： |
| 投稿时间：2016-05-11修订日期：2016-05-11 |
| 基金项目: |
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| Apply the QLAB and VVI technology to assess the right ventricular function in patients with obstructive sleep apnea syndrome |
| Sun Pin |
| (Cardiac Ultrasound,Qingdao University Hospital) |
| Abstract: |
| Objective: To observe the right ventricular myocardial strain characteristics in patients with obstructive sleep apnea syndrome, to explore their clinical significance and clinical significance of the QLAB and velocity vector imaging (VVI) in the right ventricular systolic function measurement in patients with obstructive sleep apnea syndrome. Methods: 45 patients with obstructive sleep apnea syndrome were enrolled, got the right ventricular each segment myocardial strain curve in apex four-chamber view by QLAB and VVI software, recorded the right ventricle overall longitudinal systolic strain (GLSRV QLAB, GLSRV VVI).Results: GLSRV QLAB and GLSRV VVI showed a significant correlation with traditional echocardiography right ventricular systolic function parameters. GLSRV QLAB and RVFAC were correlated (r = 0.832, P < 0.001), GLSRV QLAB and TAPSE were correlated (r = 0.868, P < 0.001), GLSRV VVI and RVFAC were correlated (r = 0.716, P < 0.001), GLSRV VVI and TAPSE were correlated (r = 0.804, P < 0.001). GLSRV QLAB and GLSRV VVI were correlated (r = 0.833, P < 0.001).Determined right ventricular systolic dysfunction by RVFAC < 35% , the best cutoff value of GLSRV - QLAB for the detection of right ventricular dysfunction was -19.852% (95% confidence interval (CI): 0.735-0.951) (AUC = 0.869, P < 0.001), with a sensitivity of 80.0% and a specificity of 86.7% . the best cutoff value of GLSRV - VVI for the detection of right ventricular dysfunction was -19.99% (95% confidence interval (CI): 0.711-0.938) (AUC = 0.849, P < 0.001), with a sensitivity of 73.3% and a specificity of 86.7%.There was no significant difference in the comparison of AUC’s by the Hanley-McNeil method (difference = 0.020, 95% CI: 0.020 0.119, P = 0.693). Conclusion: GLSRV VVI and GLSRV QLAB could evaluate the right ventricular function in patients with obstructive sleep apnea syndrome, and could provide a new reliable approach for the assessment of right ventricular function. |
| Key words: : Two-dimensional speckle tracking imaging Obstructive sleep apnea syndrome Ventricular function, right Strain |
