摘要: |
目的 探讨超声造影引导下实施激光消融术治疗小肝癌的应用价值。方法选择2011 年5 月至2014 年6 月我院收治的100例小肝癌患者,随机分成A组(n=50)与B组(n=50),其中A组行开腹手术切除治疗,B组则采用超声造影引导下实施激光消融术治疗,比较分析两组治疗效果。 结果 治疗1个月后,A组及B组的根治有效率均为100%。在3年的随访过程中,A组肿瘤复发率为16% ,B组肿瘤复发率为36% ,两组肿瘤复发率比较差异有统计学意义(P<0.05)。A组疼痛、发热、腹腔出血、感染等术后并发症发生率明显高于B组并发症发生率 (P<0.05)。A组与B组1年、2年、3年的生存率比较差异没有显著性意义。结论 超声造影引导下实施激光消融术与开腹手术切除治疗小肝癌各有优势,在医院医疗条件允许的情况下, 前者可部分替代后者。 |
关键词: 超声造影 小肝癌 激光消融治疗 肝切除术 临床疗效 |
DOI: |
投稿时间:2016-05-19修订日期:2016-07-11 |
基金项目:河北省2015年度医学科学研究重点课题计划(超声造影在激光消融术治疗小肝癌疗效评估中的临床应用) |
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Effects of Guided laser ablation guided by ultrasound on small hepatocellular carcinoma |
WANG HAIXIA |
(hebei province people's cancer hospital) |
Abstract: |
Objective To compare the effectiveness of Guided laser ablation guided by ultrasound and surgical resection as an initial treatment for patients with small hepatocellular carcinoma(HCC).Methods Between May 2011 and June 2014, 100 patients with small HCC were divided at random into two groups :A group (n=50)and B group (n=50) to undergo surgical resection or Guided laser ablation guided by ultrasound respectively .Results After 1 months of treatment, the effective cure rate of A group and B group were 100%. During 3 years of follow-up, the recurrence rate was 16% in A group, B group, the tumor recurrence rate was 36%, two groups of tumor recurrence rate was statistically significant (P < 0.05). A group of pain, fever, abdominal bleeding, infection and the incidence of postoperative complications was significantly higher than the complication rate of group B (P<0.05). The difference between the A group and B group the survival rate of 1 years, 2 years, 3 years is not significant. Conclusion Guided by ultrasound guided laser ablation and open surgical resection of small hepatocellular carcinoma has advantages, in the case of hospital medical conditions permit, the former can be partly replaced by the latter. |
Key words: Contrast enhanced ultrasound small hepatocellular carcinoma laser ablation liver resection clinical effect |