| 摘要: |
| 目的 分析原发性甲状旁腺功能亢进症(PHPT)患者心脏结构及功能特点,并探讨相关影响因素。 |
| 关键词: 原发性甲状旁腺功能亢进症 超声心动图 甲状旁腺激素 |
| DOI： |
| 投稿时间：2016-05-29修订日期：2017-04-05 |
| 基金项目:首都医科大学基础-临床科研合作基金(No. 14JL87) |
|
| Analysis of Echocardiography Characteristics of PrimaryHyperparathyroidism |
| SONG Xiu-xia,JIANG Tao |
| (Department of Endocrinology,Beijing Shijitan Hospital,Capital Medical University) |
| Abstract: |
| Objective To analyze the echocardiography characteristics of primary hyperparathyroidism(PHPT) and discuss the related factors with the cardiac structure and functions. Methods Left ventricular end-diastolic diameter (LVDd), interventricular septum diastolic thickness(IVSdT), E/A and LVEF were measured by echocardiography in 78 patients with PHPT. Left ventricular mass index(LVMI) was calculated. Correltion analysis was made within iPTH, serum Ca2 levels and echocardiography related indicators. Results The incidences of left ventricular hypertrophy, myocardial or valvular calcification,and reduction of left ventricular diastolic function in observation group were higher than those in control group(P values <0.05). In observation group, IVSdT and LVMI were higher than those in control group(1.19±0.10)cm vs (1.09±0.07)cm,(150.21±45.32) g/m2 vs (106.21±12.19)g/m2 (P values <0.05). LVEF: (62.3±7.2)% vs (66.5±3.7)%(P value>0.05). Correlation analysis showed that iPTH levels positively correlated with LVDd, IVSdT, LVMI and negatively correlated with E/A; Ca2 levels positively correlated with cardiac valvular calcification rate, and negatively correlated with E/A(P value<0.05). Conclusion Changes in cardiac structure and function are more likely to occur in PHPT patients, as left ventricular hypertrophy, diastolic dysfunction, and cardiac valvular calcification rate increasing. These changes may associated with high levels of iPTH and Ca2 . |
| Key words: ]: Hyperparathyroidism, Echocardiography, Parathyroid hormone |
