| 摘要: |
| 乳腺癌是女性最常见的恶性肿瘤之一, 其发生、发展过程中大多伴随基因异常表达。癌基因表达从不同角度反映了乳腺癌的恶性生物学行为，并引起组织病理学改变，进而形成多种影像学表现。因此,越来越多的学者发现乳腺癌超声形态学表现与分子免疫组化指标之间存在一定相关性，通过乳腺癌的超声及超声造影征象可以预测某些分子免疫组化指标的表达及其预后。本文主要对乳腺癌超声及超声造影表现与ER、PR、C-crb B -2及Ki-67表达的相关性研究进行综述。 |
| 关键词: 乳腺癌 超声 超声造影 分子免疫组化指标 |
| DOI： |
| 投稿时间：2016-07-21修订日期：2016-10-22 |
| 基金项目: |
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| Ultrasound Diagnosis of Breast Cancer and The Correlation between Molecular Immunological Index of Breast Carcinoma |
| Wang Yating,Yao Lanhui |
| (Department of Abdominal Ultrasound,the First Affiliated Hospital of Xinjiang Medical University) |
| Abstract: |
| Breast cancer is one of the most common female malignant tumors．The occurrence and development of breast cancer are often accompanied by abnormal gene expression．Oncogene expression reflects the malignant biological behavior of breast cancer from different perspectives. So, more and more scholars have found that there is a certain correlation between ultrasonographic morphologic features and molecular immunological index of breast cancer, expression and prognostic of molecular immunological index can be predicted by ultrasound and contrast enhanced ultrasound signs of breast cancer. This review summarized previous related studies and explored ultrasound and contrast enhanced ultrasound as a noninvasive predictor for ER、PR、C-cerb B -2 and Ki -67. |
| Key words: Breast carcinoma ultrasound Contrast enhanced ultrasound Molecular immunological index |
