Objective To assess the clinical value of shear wave elastography (SWE) in assessing the ablated zone of breast benign nodules treated with microwave ablation (MWA). Methods A total of twenty-three patients with twenty-five breast benign nodules underwent MWA. Color doppler flow imaging (CDFI), contrast-enhanced ultrasound (CEUS) and SWE were performed before and after MWA. Compared with CEUS, the accuracy of SWE in assessing the ablated zone of MWA was analysed. Results After MWA, The ablated zone showed no enhancement on CEUS and represented as red mixed with yellow on SWE. The difference between the ablated size measured with SWE and CEUS was not statistically significant (P >0.05). The values of Yong modulus including (Emax, Emean, Esd, Eratio) of the ablated zone were significant increased compared with the preoperative (P<0.0001). Conclusions SWE can accurately show the coagulation range and quantitatively analyze the change of stiffness after MWA, and is supposed to become a noninvasive and effective method to evaluate ablated zone of breast nodules treated with MWA.