| 摘要: |
| 目的 探讨实时剪切波弹性成像（SWE）技术在评估乳腺良性结节微波消融（MWA）效果的应用价值。
方法 对23例乳腺良性结节患者（共25个结节）行微波消融治疗，分别于治疗前后行常规超声、超声造影（CEUS）及SWE检查，测量CEUS与SWE显示的有效消融区横切面及纵切面最大径；测量消融区的杨氏模量值，包括最大弹性值Emax、平均弹性值Emean、弹性标准差Esd及病灶／脂肪弹性比Eratio。
结果 MWA术后，CEUS显示有效消融区无造影剂灌注，SWE显示消融区以红黄相间的不均匀彩色改变为主，与周围组织分界清晰，两种方法获得的消融区横切面及纵切面最大径均无统计学差异（P >0.05）。消融区杨氏模量值（Emax、Emean、Esd及Eratio）较术前相比，均有显著增加（P<0.0001）。
结论 SWE可较准确地反映乳腺结节MWA术后的消融范围，并能够定量分析消融区硬度变化，有望成为无创、有效评价消融效果的方法。 |
| 关键词: 超声造影 弹性成像 剪切波 微波消融 乳腺结节 |
| DOI： |
| 投稿时间：2016-08-10修订日期：2016-08-10 |
| 基金项目:国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| The clinical value of shear wave elastography in assessing the breast benign nodules treated with ultrasound-guided percutaneous microwave ablation |
| Li Ao,Peng Xiaojing |
| (Department of Ultrasound, the First Affiliated Hospital with Nanjing Medical University) |
| Abstract: |
| Objective To assess the clinical value of shear wave elastography (SWE) in assessing the ablated zone of breast benign nodules treated with microwave ablation (MWA). Methods A total of twenty-three patients with twenty-five breast benign nodules underwent MWA. Color doppler flow imaging (CDFI), contrast-enhanced ultrasound (CEUS) and SWE were performed before and after MWA. Compared with CEUS, the accuracy of SWE in assessing the ablated zone of MWA was analysed. Results After MWA, The ablated zone showed no enhancement on CEUS and represented as red mixed with yellow on SWE. The difference between the ablated size measured with SWE and CEUS was not statistically significant (P >0.05). The values of Yong modulus including (Emax, Emean, Esd, Eratio) of the ablated zone were significant increased compared with the preoperative (P<0.0001). Conclusions SWE can accurately show the coagulation range and quantitatively analyze the change of stiffness after MWA, and is supposed to become a noninvasive and effective method to evaluate ablated zone of breast nodules treated with MWA. |
| Key words: Contrast-enhanced ultrasound Elastography Shear wave Microwave ablation Breast nodule |
