With major developments in both contrast media and ultrasound equipment,Left heart contrast echocardiography has evolved rapidly in the last decade．The technology can improve the feasibility, repeatability and accuracy of echocardiographySto evaluate left ventricular structure and function in many cases. By quantifying myocardial blood flow at the tissue level,MCE can assess myocardial perfusion in both acute myocardial infarction and chronic ischemic heart disease．Detecting differences between normal and reduced microvascular volume in necrotic or ischemic myocardium,MCE can identify the extent and severity of myocardial contrast defects．Microbubble velocity is the strong predictor of myocardial viability and recovery of function after reperfusion treatment．LVO and EBD can evaluate left ventricular function and structure more accurately .Developing field of Left heart contrast echocardiography is moving from diagnostic technique to therapeutics．