| 摘要: |
| 目的：分析周围型肺鳞癌及肺腺癌的造影增强模式及声学造影定量参数，探讨周围型肺鳞癌及肺腺癌的造影表现特征。
方法：回顾分析经超声造影后穿刺活检病理证实的52例周围型肺鳞癌和58例周围型肺腺癌的超声造影增强表现，并应用QLAB软件制作时间－强度曲线(TIC)，获得声学造影定量参数。
结果：1、不均匀增强、低增强是两组病例造影后的共同主要表现，其出现率在肺鳞癌组分别为76.9%，86.5%；肺腺癌组67.2%，75.9%；2、周围型肺鳞癌以局部—整体型增强模式为主（37/52），可见整体增强型及周边始增型；周围型肺腺癌以周边始增型模式为主（33/58），可见整体增强型及血管样始增型；3、局部无增强是周围型肺鳞癌造影后的特征性表现，该表现与肺腺癌组差异有统计学意义（P<0.05）；4、两组病例TIC曲线均呈“尖峰型”，周围型肺鳞癌以“速升缓降”表现为主，周围型肺腺癌以“速升速降”表现为主。周围型肺鳞癌组AT、T?均短于腺癌组，α大于腺癌组，两组间比较差异均有统计学意义（P<0.05），而在TTP 、RT 、BI、EI、PI 及β两组间比较差异均无统计学意义（P>0.05）。
结论：分析超声造影增强表现的特点及声学造影定量参数的不同，对周围型肺鳞癌及肺腺癌的诊断有一定的提示意义。 |
| 关键词: 肺肿瘤 超声造影 |
| DOI： |
| 投稿时间：2016-09-06修订日期：2016-10-16 |
| 基金项目:徐州市科技计划项目（KC15SH019） |
|
| Preliminary study on contrast-enhanced ultrasound for peripheral pulmonary squamous cell carcinoma and pulmonary adenocarcinoma |
| QI -Peijun |
| (Department of Ultrasound,the Affiliated Hospital of Xuzhou Medical University) |
| Abstract: |
| Objective To investigate the characteristics of contrast-enhanced ultrasound of peripheral pulmonary squamous cell carcinoma and pulmonary adenocarcinoma by analyzing the patterns of contrast-enhanced ultrasound and the quantitative parameters of acoustic contrast. Methods The sonographic features of contrast-enhanced ultrasound of 52 cases with peripheral pulmonary squamous cell carcinoma and 58 cases with peripheral pulmonary adenocarcinoma were analyzed retrospectively, that confirmed by puncture biopsy after contrast-enhanced ultrasound. QLAB software was used to draw time-intensity curve (TIC) and the acoustic contrast quantitative parameters were recorded at the same time. Results 1. Inhomogeneous enhancement and hypo-enhancement were the main manifestations of contrast-enhanced ultrasound of the two groups of patients, the rate of occurrence in peripheral pulmonary squamous cell carcinoma were 76.9%, 86.5%, and 67.2%, 75.9% in peripheral pulmonary adenocarcinoma, respectively. 2. The main performance of contrast-enhanced ultrasound of peripheral pulmonary squamous cell carcinoma were partial-whole enhancement mode (37/52), besides the showing of the overall enhancement and peripheral enhancement beginning type; the main performance of contrast-enhanced ultrasound of peripheral pulmonary adenocarcinoma were peripheral enhancement beginning mode (33/58), besides the overall enhancement and the vascular morphology enhancement beginning pattern. 3. Local none-enhanced pattern was the characteristic manifestation of peripheral pulmonary squamous cell carcinoma, and the difference was statistically significant compared with pulmonary adenocarcinoma (P<0.05). 4. TIC curves of two groups were presented “spike type”, the main performance of peripheral pulmonary squamous cell carcinoma was “speed up and slow down”, while peripheral pulmonary adenocarcinoma was mainly manifested as “steep in rise and drop down”. AT and T? of peripheral pulmonary squamous cell carcinoma were both shorter than that of peripheral pulmonary adenocarcinoma, while α was greater than that of peripheral pulmonary adenocarcinoma, the differences between the two groups were statistically significant (P<0.05). The differences of TTP, RT, BI, EI, PI and β between the two groups were not statistically significant (P>0.05). Conclusions The analysis of the features of contrast-enhanced ultrasound and the differences of the quantitative parameters of acoustic contrast can provide certain significance in the diagnosis between peripheral pulmonary squamous cell carcinoma and pulmonary adenocarcinoma. |
| Key words: Pulmonary neoplasm Contrast-enhanced ultrasound |
