ABSTRACT Objective To explore the relationship of fetal congenital heart disease with maternal age. Methods Retrospectively analysis the prenatal ultrasound and postnatal follow-up results of 11，215 cases. The subjects were divided into four groups according to the gestational age，namely group A≤23 years old，group B 24 to 29 years old，group C 30 to 34 years old，group D≥35 years. Statistics the type of fetal congenital heart disease and the incidence of each group and calculate the four groups’ overall incidence of fetal congenital heart diseases and evaluate them. Results 106 fetal congenital heart disease cases were detected in 11，215 cases fetuses，including 101 cases were detected by prenatal ultrasound examination，five cases were detected by the postnatal echocardiography，prenatal ultrasound detection rate is 95.3%，congenital heart disease overall incidence is 9.4‰. The incidences of fetal congenital heart disease of four groups were 11‰，8.8‰，8.1‰，13‰. There were no statistical differences for the rates of four overall incidences . Ventricular septal defect is the highest incidence disease, the simple ventricular septal defect in 24 cases accounted for 22.6%, combined with other cardiac malformations in 10 cases accounted for 9.4%; followed by pulmonary artery stenosis in 14 cases accounted for 13%, with heart malformation in 10 cases (including 9 cases with tetralogy of Fallot). Conclusion there is no difference in the incidence of the congenital heart disease in different pregnant age. Regular prenatal ultrasound examination is essential to every pregnant woman.