| 摘要: |
| 目的 探讨胎儿先天性心脏病与孕妇妊娠年龄的关系。方法 回顾性分析11215例孕妇的产前超声检查和产后随访结果，按照孕妇妊娠年龄将研究对象分成四组，即A组≤23岁，B组24~29岁，C组30~34岁，D组≥35岁，分别统计四组中胎儿先天性心脏病的类型和发病率，计算并比较四组胎儿先天性心脏病的总体发病率。结果 在11215例受检胎儿中，共检出先天性心脏病胎儿 106例，其中101例由产前超声检出，5例由产后超声心动图检出，产前超声检出率95.3%，先天性心脏病总发病率9.4‰。A、B、C、D组胎儿先天性心脏病发病率分别为11‰、8.8‰、8.1‰、13‰，四组总体发病率比较，差异无统计学意义。室间隔缺损发病率最高，单纯性室间隔缺损24例占22.6%，合并其他心内畸形10例占9.4%；其次为肺动脉狭窄14例占13%，合并心内畸形10例（含法洛四联症9例）。结论 不同妊娠年龄孕妇的胎儿先天性心脏病发病率没有差别，每个年龄段孕妇定期的产前超声检查都必不可少。 |
| 关键词: 超声检查 胎儿 先天性心脏病 孕妇年龄 |
| DOI： |
| 投稿时间：2016-09-21修订日期：2017-07-13 |
| 基金项目:国家卫生计划生育委员会2013-2014年度临床医学重点专科建设项目 |
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| Explore the Relationship of Fetal Congenital heart disease with Maternal Age |
| Zhang Xiao-lin |
| (People's Hospital of Zhengzhou University) |
| Abstract: |
| ABSTRACT Objective To explore the relationship of fetal congenital heart disease with maternal age. Methods Retrospectively analysis the prenatal ultrasound and postnatal follow-up results of 11，215 cases. The subjects were divided into four groups according to the gestational age，namely group A≤23 years old，group B 24 to 29 years old，group C 30 to 34 years old，group D≥35 years. Statistics the type of fetal congenital heart disease and the incidence of each group and calculate the four groups’ overall incidence of fetal congenital heart diseases and evaluate them. Results 106 fetal congenital heart disease cases were detected in 11，215 cases fetuses，including 101 cases were detected by prenatal ultrasound examination，five cases were detected by the postnatal echocardiography，prenatal ultrasound detection rate is 95.3%，congenital heart disease overall incidence is 9.4‰. The incidences of fetal congenital heart disease of four groups were 11‰，8.8‰，8.1‰，13‰. There were no statistical differences for the rates of four overall incidences . Ventricular septal defect is the highest incidence disease, the simple ventricular septal defect in 24 cases accounted for 22.6%, combined with other cardiac malformations in 10 cases accounted for 9.4%; followed by pulmonary artery stenosis in 14 cases accounted for 13%, with heart malformation in 10 cases (including 9 cases with tetralogy of Fallot). Conclusion there is no difference in the incidence of the congenital heart disease in different pregnant age. Regular prenatal ultrasound examination is essential to every pregnant woman. |
| Key words: Ultrasonography Fetus Congenital heart disease Maternal age |
