Objective To analyze the left ventricular index differences of patients with cirrhosis by 2D speckle tracking technology. Methods 68 cases with cirrhosis in our hospital were randomly selected. According to Child classes, 68 cases were divided into A, B, C three grade groups, while 28 healthy subjects as a control group. With the application of 2D speckle tracking technology, all the patients were tested under the on-site operations. We obtained the highest value of systolic 16 horizontal, vertical directions and three-dimensional in left ventricular from three experiments and the control groups, we could analyse the differences of index between various Child classification of liver cirrhosis. Result The systolic pressure, diastolic pressure and pulse pressure of three cirrhosis groups were lower than the control group, but the heart rate were higher, which indicated the difference was statistically significant(P<0.05); In addition to the highest systolic value of apical side wall segment of left ventricular, the highest systolic values of the other cross-sections and longitudinal sections of three-dimensional directions from Child A, B, C three grade cirrhosis experiment groups were lower than the control group, which demonstrated the difference was statistically significant(P<0.05); After each pairwise comparison of the maximum systolic value of apical segment, intermediate segment and basal segment of left ventricular from three experiment groups, we found that the lowest level group was Child C while Child A was the highest, and the difference was statistically significant(P<0.05). Conclusion The part of the left ventricle in patients with cirrhosis had segmental contractility complications, and with the higher Child series(C level>B Level >A Level), more sections of left ventricular segments will reduce shrink force, and its contractile force will decline further.