| 摘要: |
| 目的 探讨“萤火虫”成像（MicroPure）技术联合声触诊组织量化（Virtual Touch Tissue Quantification，VTQ）技术在甲状腺结节诊断中的应用价值。方法 对72例患者78个甲状腺结节术前分别行常规超声、MicroPure、VTQ成像技术检查，以病理结果为金标准，分别计算MicroPure技术、VTQ技术、及两者联合诊断甲状腺结节的敏感性、特异性、准确性、阳性预测值、阴性预测值。结果 应用MicroPure 技术对甲状腺结节内微钙化显示率较常规灰阶超声高，差异具有统计学意义（P=0.008）；使用MicroPure技术、VTQ技术，及两种技术结合诊断甲状腺癌的敏感性分别为66.7%、82.4%、88.9%，特异性分别为70.0%、68.1%、71.0%，准确性分别为70.0%、71.5%、72.8%、阳性预测值分别为66.7%、66.7%、64.0%、，阴性预测值分别为70.0%、83.3%、91.7%。结论 MicroPure联合VTQ技术在甲状腺结节鉴别诊断中具有较高的临床应用价值。 |
| 关键词: 甲状腺结节 微钙化 萤火虫成像技术 声触诊组织量化技术 |
| DOI： |
| 投稿时间：2016-10-27修订日期：2016-10-27 |
| 基金项目:哈尔滨医科大学创新科学研究资助项目 |
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| The Application Value of MicroPure Imaging Method combined with Virtual Touch Tissue Quantification(VTQ) in Diagnosis of Thyroid Nodules |
| Du Lin-yao,Zhou Xian-Li |
| (Department of Ultrasonography in Abdomen, Inpatient Department, the Second Affiliated Hospital of Harbin Medical University) |
| Abstract: |
| Objective To investigate the diagnostic value of the MicroPure Imaging Method combined with Virtual Touch Tissue Quantification(VTQ) technology in patients with thyroid nodules. Methods Seventy-two patients with seventy-eight thyroid nodules underwent conventional ultrasound、micropure technology and virtual touch tissue quantification(VTQ) technique respectively before operation.Taking pathological results as golden standard, sensitivity, specificity, accuracy, positive predictive value（PPV), negative predictive value（NPV) were caculated.Results The showed rate of micro-calcification in thyroid nodules by the using of micropure technology is higher than that of conventional ultrasound singly. There were significant differences in the detection rate of the two ways (P = 0.008).The sensitivity of using micropure, VTQ and micropure combined with VTQ technology were 66.7%, 82.4%, 88.9% respectively,the specificity were 70.0%, 68.1%, 71.0% respectively, the accuracy were 70.0%, 71.5%, 72.8% respectively,the PPV were 66.7%, 66.7%, 64.0% respectively，the NPV were 70.0%, 83.3%, 91.7% respectively. Conclusion The combination of micropure and VTQ technology have highly clinical application value for differential diagnosis the benign and malignant thyroid nodules. |
| Key words: Thyroid nodule Micro-calcification MicroPure Imaging Virtual Touch Tissue Quantification |
