| 摘要: |
| 目的 运用室壁分层分析技术评价超重、肥胖患者左室心肌纵向应变(LS),并分析其影响因素。方法 根据体重指数(BMI)将受试者分为正常组、超重组及肥胖组,每组34人,运用二维斑点追踪成像(2D-STI)技术分析比较三组心脏功能变化。结果 三组三层心肌LS均存在梯度特征,即心内膜下心肌(Endo)＞中层心肌(Mid)＞心外膜下心肌(Epi)(P<0.01)；与正常组比较,肥胖组各层心肌LS减低(P<0.05)；逐步回归分析发现,BMI与LS-Endo、LS-Mid、LS-Epi独立相关,腰臀比(WHR)与LS-Endo、LS-Mid独立相关(P<0.05)。结论 三组左室壁三层心肌LS均存在梯度特征。肥胖患者左室心肌纵向收缩功能受损。BMI、WHR可能是超重、肥胖患者心脏纵向收缩功能的独立影响因素。 |
| 关键词: 体重指数 室壁分层分析 纵向应变 游离脂肪酸 |
| DOI： |
| 投稿时间：2016-11-22修订日期：2017-01-09 |
| 基金项目:四川省卫生厅科研课题 |
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| Left ventricular longitudinal strain in overweight and obese population by layer-specific deformation analysis |
| ZHANG Yanmei,HUANG He |
| (Department of Cardiology,West China Hospital,Sichuan University;Now in Department of Ultrasonography, No.416 Hospital of China National Nuclear Corporation) |
| Abstract: |
| Objective This study was aimed to evaluate left ventricular longitudinal strain(LS) in overweight and obese population by layer-specific deformation analysis, and to investigate possible influence factors of LS. Methods Two-dimensional speckle tracking imaging(2D-STI) was performed on enrolled healthy, overweight and obese groups(34 subjects in each group) to analyze cardiac function. Results Gradient feature of LS across left ventricular wall was among three groups, that was subendocardial myocardial layer>mid-myocardial myocardial layer>subepicardial myocardial layer(P<0.01). Compared with healthy group, the three-layer LS decreased in obese group(P<0.05). Stepwise regression analysis revealed that BMI was independently correlated with LS-Endo, LS-Mid, LS-Epi. Waist to hip ratio(WHR) was independently correlated with LS-Endo, LS-Mid(P<0.05). Conclusion Gradient feature of LS across left ventricular wall was among three groups. Myocardial longitudinal systolic function was impaired in obese group. Moreover, BMI and WHR may be independent influence factors of longitudinal systolic function in overweight and obese population. |
| Key words: body mass index layer-specific deformation analysis longitudinal strain free fatty acid |
