| 摘要: |
| 目的 应用声触诊组织量化成像技术(VTIQ)检测乳腺浸润性导管癌的剪切波速度(SWV)，分析SWV与浸润性导管癌预后因素的相关性。方法 回顾性分析经手术或粗针穿刺活检证实的单病灶乳腺浸润性导管癌患者101例，术前均行VTIQ检查测得肿块的SWV,记录临床TNM分期、组织学分级、ER、PR、Her2、Ki-67、p53等情况，并分析SWV与上述指标的相关性。结果 单因素相关性分析结果显示：SWV与临床TNM分期（r=0.668, P<0.001）、组织学分级（r=0.677, P<0.001）、ER（r=-0.250, P=0.012）、Her2（r=0.298, P=0.002）、Ki-67（r=0.505, P<0.001）具有相关性；结论 应用VTIQ技术检测乳腺浸润性导管癌的SWV可以预测肿瘤预后因素，为临床治疗选择、预后判断等提供更多参考。 |
| 关键词: 乳腺浸润性导管癌 声触诊组织量化成像技术 预后因素 |
| DOI： |
| 投稿时间：2016-11-30修订日期：2016-11-30 |
| 基金项目:上海市科委生物医药领域科技支撑项目（14441900900）；上海市科委引导项目（15411969000） |
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| Correlation analysis between novel technique of virtual touch tissue imaging quantification and prognostic indicators in breast invasive ductal carcinoma |
| liuqing,guolehang |
| () |
| Abstract: |
| Purpose: To apply novel virtual touch tissue imaging quantification（VTIQ）technique to detect SWV of invasive breast ductal carcinoma and analyze correlation between SWV and prognosis factors of invasive ductal carcinoma.Method: 101 patients with single lesion invasive breast ductal carcinoma were confirmed via operation or core needle biopsy by conducting retrospective analysis. VTIQ check was conducted before operation to detect lump’s SWV, record clinical TNM staging, histological grade,ER,PR,Her2,Ki-67 and p53 etc and further analyze correlation between SWV and above mentioned indexes. Results: The single factor correlation analysis showed that SWV showed correlations with clinical TNM staging（r=0.668, P<0.001）, histological grade （r=0.677, P<0.001）,ER（r=-0.250, P=0.012）,Her2（r=0.298, P=0.002）and Ki-67（r=0.505, P<0.001）.
Conclusion:The VTIQ technology can be applied to detect SWV of invasive breast ductal carcinoma, which can predict prognosis factor of tumors and provide more references for clinical treatment and prognosis etc. |
| Key words: Invasive ductal carcinoma of the breast Virtual touch tissue imaging quantification Prognosis factors |
