Abstract:Objective To explore the relationship between Acoustic Radiation Force Impulse (ARFI) and Hepatic Fibrosis in order to reduce patients" postoperative complications after liver cancer surgery.Methods According to the liver fibrosis stage standard, one hundred and fifty patients with liver carcinoma were analyzed about clinical data and the extent of liver fibrosis stage was quantitatively analyzed by ARFI. Patients were divided into fibrosis S0, S1, S2, S3, S4 five groups. One-way ANOVA were implemented to analyze the SWVs (Shear Wave Value) in these groups. Then the relationship between ARFI and Hepatic Fibrosis was analyzed. Furthermore, ROC curve based on SWV was performed to identify the diagnosis of hepatic fibrosis. In the end, the postoperative complications was evaluated through SWVS and pathological reports and the sensitivity and specificity were compared to imply the application of ARFI. Results The SWVs in the S0, S1, S2, S3 and S4 groups were significantly increasing. The differences was statistically significant (F=54.678,P<0.05). Correlation analysis has shown a positive correlation between SWV and liver fibrosis stage (r=0.76,P=0.000). The ROC of the liver fibrosis diagnosis by ARFI showed that the AUC was 0.885, the best critical value was 1.315, and the sensitivity was 94.6% but specificity was 64.5%. Further analysis found that the prediction of postoperative complications by ARFI and pathological reports were similar (ARFI: Sensitivity 94.4%, Specificity 92.7%; pathological reports: Sensitivity 98.1%, Specificity 94.8%). Conclusion ARFI is helpful to improve the prediction of liver fibrosis in liver carcinoma patients. It provides impotent information for reduction of postoperative complications.