| 摘要: |
| 目的 研究乙醇消融和射频消融治疗甲状腺囊实性结节方面的疗效，并比较两种方法的治疗效果。方法 回顾性分析我院2014年2月至2015年6月在我院接受乙醇消融或射频消融的患有单个甲状腺囊实性结节的患者的住院资料，依据患者接受治疗方法的不同，将患者分为乙醇组(n=46)和射频组(n=49)。分析比较两组患者接受治疗后3个月、6个月、9个月及12个月甲状腺结节体积减少的情况；观察两种治疗方法在甲状腺结节不同囊实性比例情况下的治疗效果，同时分析不同体积情况下两种治疗方法的治疗效果。并对两组患者出现不良反应情况进行分析比较。结果 两组患者甲状腺结节均减小，但射频组患者结节体积缩小率（90.78±7.47）%明显高于乙醇组（69.71±4.95）%，差异具有统计学意义(P<0.05)；随着甲状腺结节体积的增大，囊实性比例的缩小，两组患者甲状腺结节体积缩小率均减小。而当结节体积大于30ml时，结节囊实性比例不足50%，乙醇组体积缩小率不足50%，治疗无效。不论结节体积及囊实性比例的大小，射频组患者结节体积缩小率均显著高于乙醇组，结果具有统计学意义（P<0.05）；两组患者出现不良反应情况未见明显差异，结果无统计学意义(P>0.05)。结论 甲状腺囊实性结节小于30ml、囊实性比大于50%，乙醇消融经济且疗效确切，可做为首选；而结节体积较大，囊实性占位不足50%应用射频消融术治疗。 |
| 关键词: 乙醇消融 射频消融 甲状腺囊实性结节 |
| DOI： |
| 投稿时间：2016-12-06修订日期：2017-02-19 |
| 基金项目:宁波市鄞州区科技计划项目（2015-96） |
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| Evaluation of Curative Effect of Ethanol Ablation and Radiofrequency Ablation in the Treatment of Thyroid Cystic Solid Nodules |
| WU Meng |
| (Department of ultrasonic medicine, Yinzhou People's Hospital, Ningbo City, Zhejiang Province) |
| Abstract: |
| Objective To study the curative effect of alcohol ablation and radiofrequency ablation in the treatment of solid nodules of the thyroid, in order to compare the therapeutic effect of the two methods. Method Retrospective analysis of hospitalized patients with single thyroid cystic nodules in our hospital from February 2014 to June 2015, who underwent ethanol ablation or radiofrequency catheter ablation. Patients were divided into ethanol group (n = 46) and radiofrequency group (n = 49) according to the different treatment methods. The volume reduction of thyroid nodules at 3 months, 6 months, 9 months and 12 months after treatment was analyzed and compared. The therapeutic effects of the two treatment methods on the different ratio of thyroid cystic solid nodules were observed and analyzed. And to analyze the therapeutic effect of the two treatment methods under different volume. And the adverse reactions of the two groups of patients were analyzed and compared. Results The thyroid nodules of the two groups were reduced, but the volume reduction rate of radiofrequency group（90.78±7.47）% was significantly higher than ethanol group（69.71±4.95）% , the difference had statistical significance (P <0.05). With the increase of the volume of thyroid nodules and reduction of cystic solidity ratio the volume reduction rate of thyroid nodules in both groups decreased, When the volume of nodules greater than 30ml and the cystic solidity ratio was less than 50%, the volume reduction rate was less than 50%, then the treatment was invalid. The nodule volume reduction rate of radiofrequency group was significantly higher than that of ethanol group (P <0.05), regardless of the proportion and volume of nodules. There was no significant difference in adverse reactions between the two groups. The results had no statistical significance (P> 0.05). Conclusion Thyroid cystic solid nodule less than 30ml, cystic solid more than 50%, ethanol ablation is economic and effective, can be used as the first choice; And larger nodules, cystic mass is less than 50% , the radiofrequency ablation can be used. |
| Key words: ethanol ablation radiofrequency ablation thyroid cystic solid nodule |
