【】 Objective TO evaluate the value of ultrasound in quantitative diagnosis of nonalcoholic fatty liver disease,and explore the correlation between liver fatty contents and metabolic syndrome、macro-vascular disease。Methods 148 patients from Physical Examination Center who were diagnosed NAFLD by ultrasound,were divided into light、medium、heavy fatty infiltration by qualitative diagnosis of ultrasound,49 were normal group。The liver fatty contents were estimated by ultrasound quantitative analysis in the object of study,and combined with BMI、BP、hematologic chemical and endocrine exams、carotid artery IMT and the clot were compared the difference in all groups,and analyzed the correlation between liver fatty contents and all the index above-mentioned。Results Adjusted by gender and age,beyond SBP、TC,other index were statistically significant (p<0.05)。liver fatty contents had significant correlation with obesity、DM、fatty metabolism、hypertension、carotid artery IMT and liver enzyme。Conclusion Ultrasonic quantitative diagnosis methods can be more accurate in estimating liver fatty contents。liver fatty contents is closely related with metabolic syndrome、carotid artery IMT。This method can provide a simple and effctive diagnostic tool in the diagnosis of fatty liver、follow-up and estimate the effectiveness in fatty liver for clinical。