| 摘要: |
| 目的 主动脉瓣狭窄(AS)患者的左室搏出量与患者的临床症状等相关,本文探讨AS患者的左室搏出量指数(SVi)与左室长轴应变的相关性。 方法 AS患者52例,三维超声心动图检测每搏输出量,根据SVi<35ml/m2将AS患者分为正常搏出量组(n=33)和低搏出量组(n=19)；通过二维斑点追踪法检测心尖四腔心切面左室总长轴应变(GLS)和左室基底段、中段、心尖段的长轴应变(BLS、MLS、ALS)以及BLS/ALS,分析SVi与GLS、左室射血分数(EF)和主动脉瓣狭窄的瓣口面积(AVA-3D)的相关性。 结果 正常搏出量组和低搏出量组两组的参数比较：EF(60.9±3.0 对 49.4±6.8,P<0.001)、GLS(-18.7±2.7 对-13.3±2.9,P<0.001)、BLS(-16.2±3.4 对 -9.8±5.6,P<0.001)、MLS(-18.7±3.2 对 -12.7±5.7,P<0.001)、ALS(-22.9±4.9 对 -19.6±6.8,P<0.045)、BLS/ALS(0.72±3.0 对 0.51±3.8,P<0.001)、峰值压力阶差PGmax(68.6±19.8 对 40.1±10.3,P<0.001)、AVA-3D(1.15±0.27 对1.08±0.26,P=0.376),SVi对GLS的相关性(r=0.799,R2=0.639,P<0.001)、对EF的相关性(r=0.788,R2=0.621,P<0.001)、对AVA-3D的相关性(r=0.204,R2=0.042,P=0.147),SVi与GLS和EF呈现良好的相关性。 结论 低搏出量主动脉瓣狭窄患者左室长轴应变减小,左室搏出量指数相关于左室的长轴应变和左室射血分数。 |
| 关键词: 主动脉瓣狭窄 超声心动图描记术 斑点追踪成像 每搏输出量 |
| DOI： |
| 投稿时间：2016-12-29修订日期：2017-01-23 |
| 基金项目: |
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| Relationship between Stroke Volume Index and Left Ventricular Longitudinal Strain in Aortic Stenosis |
| sunbugao,zhang ning |
| (nanjing drum tower hospital) |
| Abstract: |
| ABSTRACT Objective Stroke volume index (SVi) has been proposed as potential value in patients with aortic stenosis (AS). The aim of this study was to evaluate the relationship between SVi measured by three dimensional echocardiography and left ventricular (LV) global longitudinal strain in patients with AS. Methods Fifty-two patients with AS underwent echocardiographic examination, including three dimensional echocardiography and two-dimensional speckle-tracking strain measurements. Patients were retrospectively grouped according to SVi (<35ml/m2) into normal stroke volume groups (n=33) and low stroke volume groups (n=19). It were calculated to LV global longitudinal strain (GLS), basal longitudinal strain (BLS), medial longitudinal strain (MLS) and apical longitudinal strain (ALS) with two-dimensional speckle-tracking echocardiography. Results There was significantly different between two groups in left ventricular ejection fraction (LVEF, 60.9±3.0 vs 49.4±6.8，P<0.001), GLS ( -18.7±2.7 vs -13.3±2.9，P<0.001), BLS（-16.2±3.4 vs -9.8±5.6，P<0.001）、MLS（-18.7±3.2 vs -12.7±5.7，P<0.001）、ALS（-22.9±4.9 vs -19.6±6.8，P<0.045） and peak transvalvular pressure gradient (PGmax, 68.6±19.8 vs 40.1±10.3，P<0.001）. SVi showed the great correlations with the outcome of LVEF（r=0.788，R2=0.621，P<0.001）and GLS（r=0.799，R2=0.639，P<0.001）. There were the correlations between SVi and aortic valve area (r=0.204，R2=0.042，P=0.147). Conclusion Among the echocardiographic measures, stroke volume index (SVi) has the strongest association with the great correlations with left ventricular global longitudinal strain and ejection fraction. |
| Key words: Aortic stenosis Echocardiography Speckle-tracking technique Stroke volume |
