|
|
|
本文已被:浏览 3113次 下载 1799次 |
|
超声造影在鉴别甲状腺结节合并钙化灶良恶性病变的价值研究 |
李宏丽 |
|
(惠州市第一人民医院) |
|
摘要: |
目的 探讨超声造影对于评价甲状腺结节合并钙化灶良恶性诊断的临床价值。方法 回顾性分析我院经手术病理证实伴有钙化灶的甲状腺结节患者92例,对比良、恶性甲状腺结节超声造影参数,分析通过超声造影诊断甲状腺结节合并钙化良恶性的准确性、特异性及敏感性。结果 51例恶性结节中,80.39%伴微钙化,弱增强及不均匀增强比例分别为82.35%、、88.24%。41例良性结节中,26.83%伴微钙化,弱增强及不均匀增强比例分别为9.76%、14.63%。恶性结节微钙化、弱增强及不均匀增强比例均显著高于良性结节,差异有统计学意义(χ2 = 24.121,30.024,30.487,P=0.031,0.020,0.007)。恶性甲状腺结节与良性甲状腺结节的峰值强度有显著性差异(P<0.05)。但两者间始增时间及达峰时间无统计学意义(P>0.05)。2名医师通过超声造影诊断甲状腺结节并钙化患者的良恶性,与病理进行比较分析,发现超声造影对有钙化甲状腺结节良恶性诊断的特异度、准确度、敏感度均较高,分别为82.4%,83.7%,86.6%。结论 超声造影对合并钙化的甲状腺结节的诊断具有较高的临床价值,准确性高,值得使用。 |
关键词: |
DOI: |
投稿时间:2017-01-05修订日期:2018-01-30 |
基金项目: |
|
Value of contrast - enhanced ultrasound in differentiating benign and malignant thyroid lesions from calcification |
LI Hong-li |
() |
Abstract: |
Abstract Objective evaluate the clinical value of ultrasonography in the diagnosis of thyroid nodules with calcified lesions. Methods retrospective analysis confirmed by surgery pathology with calcifications of 92 patients with thyroid nodules, benign and malignant thyroid nodule ultrasound imaging parameters analysis, analysis by contrast-enhanced ultrasonography diagnosis of thyroid nodules with calcification of benign and malignant accuracy, specificity and sensitivity. Results the 80.39% of 51 cases were microcalcification, and the proportion of weak enhancement and non-uniform enhancement was 82.35% and 88.24% respectively. Among the 41 benign nodules, 26.83% had microcalcification, and the proportion of weak enhancement and non-uniform enhancement was 9.76% and 14.63% respectively. The ratio of microcalcification, weak enhancement and inhomogeneity of malignant nodules was significantly higher than that of benign nodules, and the difference was statistically significant (χ2= 24.121, 30.024, 30.487, P=0.031,0.020,0.007). The peak intensity of malignant thyroid nodules and benign thyroid nodules was significantly different (P<0.05). However, there was no statistical significance between the time between the two and the peak time (P>0.05). Two doctors by contrast-enhanced ultrasound diagnosis of benign and malignant calcification in patients with thyroid merger, compared with the pathological analysis, found that the ultrasonic imaging of the calcification of benign and malignant thyroid nodule diagnosis specific degrees, high accuracy and sensitivity, respectively, 82.4%, 83.7%, 86.6%. were microcalcification, and the proportion of weak enhancement and non-uniform enhancement was 82.35% and 88.24% respectively. Among the 41 benign nodules, 26.83% had microcalcification, and the proportion of weak enhancement and non-uniform enhancement was 9.76% and 14.63% respectively. The ratio of microcalcification, weak enhancement and inhomogeneity of malignant nodules was significantly higher than that of benign nodules, and the difference was statistically significant (χ2= 24.121, 30.024, 30.487, P=0.031,0.020,0.007). The peak intensity of malignant thyroid nodules and benign thyroid nodules was significantly different (P<0.05). However, there was no statistical significance between the time between the two and the peak time (P<0.05). Two doctors by contrast-enhanced ultrasound diagnosis of benign and malignant calcification in patients with thyroid merger, compared with the pathological analysis, found that the ultrasonic imaging of the calcification of benign and malignant thyroid nodule diagnosis specific degrees, high accuracy and sensitivity, respectively, 82.4%, 83.7%, 86.6%. Conclusion Ultrasonography has high clinical value and high accuracy in the diagnosis of calcified thyroid nodules. |
Key words: Ultrasound contrast agent calcification lesions thyroid nodules, benign and malignant |
|
|
|
|
|