| 摘要: |
| 目的 探讨瞬时波强技术结合高频超声评价2型糖尿病患者桡动脉弹性及结构中的临床应用价值。方法 选取84例2型糖尿病患者并按照病程分为A、B两组，A组（病程≤10年）42例，B组（病程＞10年）42例，另选取42例健康志愿者为正常对照组。应用瞬时波强技术分别检测三组桡动脉弹性，同时应用高频超声测量其双侧桡动脉内中膜厚度（rIMT），并将获取的数据进行统计学分析。结果 A、B两组的血管顺应性（AC）、瞬时加速度波强（W1）、瞬时减速度波强（W2）均低于正常对照组；B组AC、W1、W2均低于A组，差异均有统计学意义（均P＜0.05）。A、B两组血管压力应变弹性（Ep）、血管硬化参数（β）、脉搏波传导速度（PWVβ）均高于正常对照组，B组Ep、β、PWV高于A组，差异均有统计学意义（均P＜0.05）。三组负向波面积（NA）比较，差异均无统计学意义。A、B两组rIMT大于正常对照组，B组rIMT大于A组，差异均有统计学意义（均P＜0.05）。结论 应用瞬时波强技术联合高频超声可客观、无创地评价2型糖尿病桡动脉弹性及结构的异常，具有重要的临床价值。 |
| 关键词: 瞬时波强技术 超声检查 糖尿病，2型 桡动脉 弹性 |
| DOI： |
| 投稿时间：2017-01-17修订日期：2017-07-22 |
| 基金项目: |
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| Assessment of radial artery wall elasticity and structure inpatients of type 2 diabetes mellitus by wave intensity and ultrasonography |
| li ting,zhang yu hong,su ben li |
| (The Second Hospital of Dalian Medical Univercity) |
| Abstract: |
| Objective To discuss the clinical value of wave intensity and high-frequency ultrasonography in evaluation of radial artery wall elasticity and structure in patients of type 2 diabetes mellitus. Methods Ａtotal of 84 patients of T2DM were enrolled and divided into two groups：group A（42 cases，the course ≤10 years）and group B（42 cases，the course ＞10 years ）.And 42 healthy subjects were enrolled as control group. WI was used to measure the elasticity parameters of radial artery in all the groups. And high-frequency ultrasonography was used to measure the intima medial thickness of both sides of the radial artery（rIMT）.The results were analyzed statistically. Results The arterial compliance （AC），accelerating wave intensity （W1） and decelerating wave intensity （W2） in group A and B were significantly lower than those in control group （all P＜0.05）. AC，W1 and W2 in group B were significantly lower than those in group A （all P＜0.05）.The vascular pressure strain elastic modulus （Ep），vascular sclerosis parameters （β） and pulse-wave velocity （PWVβ） in group A and B were significantly higher than those in control group （all P＜0.05）. Ep，β，PWVβ in group B were significantly higher than those in group A （all P＜0.05）.There was no statistical difference of the negative area （NA）among 3 groups.The rIMT in group A and B were significantly higher than that in control group （all P＜0.05） and the rIMT in group B was higher than that in group A （P＜0.05）. Conclusion WI and high-frequency ultrasound can evaluate the elasticity and the structure of radial artery in T2DM patients objectively and non-invasively and have important clinical value. |
| Key words: Wave intensity Ultrasonography Diabetes mellitus,type 2 Radial artery Elasticity |
