| 摘要: |
| 摘 要 目的 探讨三维超声测量GSM/TPV比值Q与缺血性脑卒中发生的相关性。方法 随机选取神经内科颈动脉斑块患者149名，排除斑块位置较深及QLAB-VPQ软件无法识别的共17名，无颅脑影像资料的25名，余107名为受试者为样本总数。据受试者颅脑的CT、MRI等影像结果将受试者分成两组，A组为脑卒中组，共66人；B组为非脑卒中组，共41人。受试者均行三维超声，通过QLAB-VPQ软件获取斑块的灰阶中位数（Gray-scale Median, GSM）及斑块体积（Total Plaque Volume，TPV），并计算出GSM与TPV的比值Q。运用统计学方法分析Q与缺血性脑卒中的相关性。 结果 A、B两组Q值进行Wilcoxon秩和检验，统计量Z=-4.857，P=0.000，差异具有统计学意义。将全部Q值采用非条件logistic回归分析，Q的OR值为1.015（1.007-1.024）。Q值可作为脑卒中的相关危险因素。结论 Q与缺血性脑卒中的发生具有一定相关性， Q值越低发生脑卒中可能性越高。 |
| 关键词: 三维超声 颈动脉斑块 灰阶中位数 斑块体积 脑卒中 |
| DOI： |
| 投稿时间：2017-01-19修订日期：2017-02-24 |
| 基金项目:深圳市未来产业专项资金CXZZ20140523105549765 |
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| The study of the correlation between the Gray-scale median(GSM)/total plaque volume(TPV) of carotid plaque and stroke with three-dimensional ultrasonography |
| tianhongtian,xujinfeng |
| () |
| Abstract: |
| Abstract：Objective This study intend to explore the correlation between stroke and the ratio Q, Gray-scale median(GSM)/total plaque volume(TPV) by using three-dimensional ultrasonography. Methods Firstly, we will randomly select 149 patients with carotid plaque in neurology, and further removing 17 patients whose plaque are too deep-rooted that cannot be detected with QLAB-VPQ, and 25 patients without brain images. The rest 107 patients become the testing samples. The testing participants will be divided into two groups according to their brain scanning images results of CT,MRI and etc. After this step, 66 patients divided into group A, labeled as Group Stroke, and 41 patients dived into group B, labeled as Group Non-stroke. All participants will be tested to get their Ratio Q, which is the value of Gray-scale Median (GSM) tested with the aid of QLAB-VPQ, and Total Plaque Volum (TPV). A methodological statistics will be applied to analysis the correlation of ration Q with stroke. Results Firstly, the rank-sum test of the ration Q of group A and group B, the statistic Z= - 4.857, and P = 0.000, and the difference is statistically significant; secondly, the OR of ratio Q is calculated as 1.015 CI (1.007-1.024) after a unconditional logistic regression analysis of ratio Q. In this way, ratio Q could be categorized as a correlated risk factor to stroke. Conclusions ratio Q is negatively correlated with stroke, in other words, the lower the Ratio Q is, the higher the risk of occurring stroke, and vice versa. |
| Key words: Three-dimensional ultrasonography Carotid plaque Gray-scale median（GSM） Total plaque volume(TPV) Stroke |
