胎儿静脉导管血流频谱参数在晚孕期妊娠期糖尿病中的研究曹云云 牛建梅 曾敏 孔晓晓 杨田 姚世发 杜硕娟
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上海交通大学附属国际和平妇幼保健院,上海交通大学附属国际和平妇幼保健院

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Study of fetal ductus venosus doppler parameter with gestational diabetes mellitus in later gestation
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Department of Ultrasound,International Peace Maternity and Child Health Hospital,Shanghai Jiao Tong University,Department of Ultrasound,International Peace Maternity and Child Health Hospital,Shanghai Jiao Tong University

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    摘要:

    目的 探讨晚孕期妊娠期糖尿病(GDM)胎儿静脉导管(DV)的频谱参数在临床中的应用价值,并分析胎儿妊娠结局。方法 选择GDM组78例为研究组,正常妊娠组136例作为对照组。应用超声检测胎儿DV频谱参数包括S、D、a、v、Tmax、S/a、PI、PLI及PVIV,将两组间参数进行分析,并对这些胎儿追踪,随访至妊娠结束,比较两组间胎龄、分娩方式、体质量及妊娠结局的关系。结果 1、GDM组胎儿DV频谱参数S、D、v 、a、Tmax测值均小于正常妊娠组,而S/a、PI、PLI及PVIV测值均高于正常妊娠组;其中S、D、v 、a、Tmax、PVIV两组间比较差别有统计学意义(P<0.05);S/a、PI、PLI两组间比较差别无统计学意义(P>0.05)。2、GDM组的胎龄及体质量均低于正常组,而剖宫产率及不良妊娠结局均高于正常组;胎龄及剖宫产率在两组间比较差别有统计学意义(P<0.05),而体质量及不良结局在两组间比较差别无统计学意义(P>0.05)。结论 应用超声监测晚孕期GDM胎儿DV的频谱参数,可为临床预测胎儿妊娠情况提供依据,在一定程度上尽可能延长妊娠时间,降低剖宫产率及不良妊娠结局的发生。

    Abstract:

    Objective To explore fetal ductus venosus(DV) Doppler parameter and application value with gestational diabetes mellitus(GDM) in later gestation. Methods Seven-eight cases blood glucose controlled well of GDM women were in research group. One hundred thirty-six cases normal pregnant women were in control group. The ventricular systole(S),ventricular diastole( D),ventricular end-systole( v),atrium systole( a), time maximum velocity (Tmax) , S/a ratio, pulsatility index(PI), preload index(PLI) and peak velocity index vein(PVIV) of DV doppler parameters were detected by ultrasound. Two groups of parameters were analyzed and followed up the fetal outcome, then gestational age, delivery way, body mass and pregnancy outcome were compared. Results In group of GDM less than normal pregnant women were compared with the S, D, v, a, Tmax parameters of fetal DV, but the S/a ratio, PI, PLI and PVIV greater than control group. The S, D, v, a, Tmax and PVIV was significant difference in two groups(P<0.05), the S/a ratio, PI and PLI was no difference(P>0.05).In group of GDM gestational age and body mass was inferior to control group, but cesarean ratio and adverse pregnancy outcomes was superior to control group. Gestational age and cesarean ratio was significant difference in two groups(P<0.05), the body mass and adverse pregnancy outcomes was no difference(P>0.05). Conclusions Through the detection of GDM fetal DV blood flow spectrum was provided in later gestation, we can predict fetal pregnancy outcomes for clinical. We can prolong pregnancy duration in certain extent, reduce cesarean ratio and adverse pregnancy outcomes.

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曹云云,牛建梅.胎儿静脉导管血流频谱参数在晚孕期妊娠期糖尿病中的研究曹云云 牛建梅 曾敏 孔晓晓 杨田 姚世发 杜硕娟[J].临床超声医学杂志,2018,20(3):

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  • 收稿日期:2017-02-07
  • 最后修改日期:2017-04-03
  • 录用日期:2017-04-18
  • 在线发布日期: 2018-03-23
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