| 摘要: |
| 目的 分析乳腺癌新辅助化疗(NAC)前后的声像图变化，探讨高频超声对NAC疗效的评估价值。方法 回顾性分析81位乳腺癌患者共87个病灶的NAC前、及NAC 2个周期后及4个周期后超声测量病灶的大小、血流特征改变，并与病理对照评估。结果 NAC前后以残余灶的最大径线、血流等级可作为NAC后评效的有效指标；与病理组织学对照其评估化疗有效的超声评价的准确率、灵敏度、特异度分别为80.5％、89.8％ 、60.7％。结论 超声对乳腺癌NAC疗效有重要评估价值，NAC前后以最大径线、血流等级为评效指标对比研究对于NAC治疗效果有重要指导价值，并与病理组织学评估化疗的有效性具有较高的一致性。 |
| 关键词: 乳腺癌 新辅助化疗 彩超 病理评价 |
| DOI： |
| 投稿时间：2017-03-22修订日期：2017-04-13 |
| 基金项目:深圳市科创委基金（JCYJ20160429185900035） |
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| The value of ultrasonography in predicting the complete remission of neoadjuvant chemotherapy |
| sulin |
| (The University of HongKong-Shenzhen Hospital) |
| Abstract: |
| Abstract：Objective：To analyze the changes of ultrasonography in breast cancer before and after neoadjuvant chemotherapy (NAC), and to evaluate the value of high frequency ultrasound in the evaluation of NAC efficacy. Methods： A retrospective analysis of 87 cases of breast cancer patients before and after NAC lesions size, blood flow, and hardness change, and compared with pathological assessment. Results： ultrasound in 6 lesions disappeared after NAC, its degree of sensitivity, specific, the accuracy is 87.5%, 65% and 81.1% respectively; The largest diameter line with residual foci, blood flow grade, elastic score changes as NAC after a review of the efficiency index, evaluation of effective chemotherapy accuracy were 79.2%, 84.9% and 94.3% respectively. The sensitivity of 95.2%, 95.6% and 97.9% respectively. Conclusion： Ultrasound has important value in assessing the effect of NAC of breast cancer, after NAC for ultrasonic elasticity score, blood flow grade evaluation effect index to evaluate residual diagnosis coincidence rate, the sensitivity of the oven is higher than with maximum diameter line for the evaluation of effect index evaluating residual foci, and histologic evaluation of the effectiveness of chemotherapy with high consistency. |
| Key words: breast cancer neoadjuvant chemotherapy color doppler ultrasound pathological response |
