Abstract:objective To analysis the application of MFM in the removal of type II submucousal fibroids by hysteroscopy or laparoscopy. Method 226 patients with type II submucousal fibroids from December 2014 to December 2016 in our hospital were collected and analyzed clinical data.According to the different surgical methods, the patients were divided into hysteroscopy group (n=114) and laparoscopic group (n=112).The MFM, tumor diameter, tumor location, operation time, intraoperative blood loss, operation costs were compared in two groups.The patients were followed up for 6 months. The changes of menstruation, anemia, recurrence and pregnancy were recorded.Result All the patients were diagnosed as benign tumor after operation.There was no significant difference in MFM, tumor diameter, tumor number and tumor location between the two groups (P>0.05).Length of the fibroids pseudocapsule to uterine mucosa, operation time, intraoperative blood loss, postoperative hemoglobin difference, hospitalization days and hospitalization costs in hysteroscopy group were lower than that in laparoscopic group(t=13.98,13.39,6.60,13.54,4.47,22.55,P<0.01).After 6 months, the improvement of menstruation was better (χ2=18.48, P<0.01), and the hemoglobin values in the two groups were normal.Conclusion Hysteroscopic resection of uterine fibroids can shorten operation time and reduce intraoperative blood loss and the economic burden of patients. Hysteroscopy treatment is safe and effective in the diameter of fibroids <65mm, and the MFM≤5mm.