Abstract:Objectives: To investigate the correlation between the coronal plane imaging features obtained by an automated breast volume scanner (ABVS) and different molecular subtypes of breast cancer. Methods: Data from 153 breast cancer patients (157 tumors) confirmed pathologically were analyzed. Each tumor was examined by ABVS for coronal plane imaging features and by immunohistochemical analysis to obtain the molecular subtype. The clinicopathological characteristics and imaging features of different molecular subtypes were compared. Results: We found significant difference in boundary, microcalcifications and indirect signs on the coronal plane between the four subtypes (P<0.05).The Luminal B and Her-2 subtypes were more commonly seen with microcalcifications (69.4% and 77.3%,respectively). Retraction phenomenon occurred more frequently in Luminal A subtype(43.7%) than in others(all P<0.05).Clear boundary was more often found in Triple-Negative subtype(27.8%).No statistically significant difference was found in clinicopathological characteristics and margin shape among the four subtypes(all P>0.05). Conclusions: The coronal plane imaging features have a certain correlation with the four breast cancer subtypes.