Objective To analyze the parameters from echocardiography in patients with coronary heart disease(CHD) and explore the correlation with cardiac function classification of NYHA. Methods The echocardiography was operated to check the level of left ventricular end systolic diameter(LVESD), left ventricular end diastolic diameter(LVEDD), left ventricular ejection fraction(LVEF), peak flow velocity of mitral valve in early diastole to peak flow velocity of mitral annulus in early diastole(E/Ea) in 166 cases of CHD, which were divided into 4 groups by cardiac function classification of New York Heart Association(NYHA): NYHA class Ⅰ group(A group, 48 cases ), NYHA class Ⅱ group(B group, 45 cases), NYHA class Ⅲ group(C group,40 cases), NYHA class Ⅳ group(D group, 33 cases), that compared with 50 normal subjects(NC group). The receiver operating characteristic(ROC) curves were figured, and the area under ROC curves(AUCs) were calculated to evaluate the diagnostic value of these items. The correlation between cardiac function classification of NYHA and LVESD, LVEDD, LVEF, E/Ea in CHD was analyzed. Results 1) The level of LVESD, LVEDD, E/Ea rose significantly and LVEF decreased obviously(P＜0.05) as the cardiac function classification of NYHA processed. 2) The AUCs of LVESD, LVEDD, LVEF, E/Ea were respectively0.888, 0.753, 0.123, 0.770. 3) There was a significant positive correlation between cardiac function classification of NYHA and LVESD, LVEDD, E/Ea, but a negative correlation with LVEF. Conclusion To monitor LVESD, LVEDD, LVEF, E/Ea with echocardiography can be used to assess the changes of cardiac function in CHD.