| 摘要: |
| 目的 对冠心病(CHD)患者心脏彩超参数进行分析,探讨其与心功能分级的相关性。方法 166例CHD患者根据美国纽约心脏病协会(NYHA)心功能分级进行分组：心功能Ⅰ级(A组48例)、心功能Ⅱ级(B组45例)、心功能Ⅲ级(C组40例)、心功能Ⅳ级(33例),同期选择50名健康体检者作为正常对照组(NC组),对两组进行心脏超声检查,比较各组左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)、二尖瓣舒张早期峰值流速/二尖瓣环舒张早期峰值流速(E/Ea)。同时,绘制ROC曲线,计算曲线下面积(AUC),以评价各指标在CHD中的诊断价值,并对心功能分级、LVESD、LVEDD、LVEF、E/Ea进行相关性分析。结果 1) 随着心功能分级的进展,LVESD、LVEDD、E/Ea显著升高,LVEF显著降低(P＜0.05)；2) 通过ROC曲线分析,LVESD、LVEDD、LVEF、E/Ea在CHD诊断中的AUC分别为0.888、0.753、0.123、0.770；3) 心功能分级与LVESD、LVEDD、E/Ea显著正相关,与LVEF显著负相关(P＜0.001)。结论 对CHD患者行心脏超声监测LVESD、LVEDD、LVEF、E/Ea可用于评价CHD心功能变化。 |
| 关键词: 冠心病,超声心动图,多普勒,心功能分级,左心室功能 |
| DOI： |
| 投稿时间：2017-04-12修订日期：2017-04-12 |
| 基金项目: |
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| Correlation analysis between cardiac function classification of NYHA and echocardiography in coronary heart disease |
| PAN Guiqin |
| (Department of Ultrasound,the 175th Hospital of PLA,Affiliated Dongnan Hospital of Xiamen University,Zhangzhou) |
| Abstract: |
| Objective To analyze the parameters from echocardiography in patients with coronary heart disease(CHD) and explore the correlation with cardiac function classification of NYHA. Methods The echocardiography was operated to check the level of left ventricular end systolic diameter(LVESD), left ventricular end diastolic diameter(LVEDD), left ventricular ejection fraction(LVEF), peak flow velocity of mitral valve in early diastole to peak flow velocity of mitral annulus in early diastole(E/Ea) in 166 cases of CHD, which were divided into 4 groups by cardiac function classification of New York Heart Association(NYHA): NYHA class Ⅰ group(A group, 48 cases ), NYHA class Ⅱ group(B group, 45 cases), NYHA class Ⅲ group(C group,40 cases), NYHA class Ⅳ group(D group, 33 cases), that compared with 50 normal subjects(NC group). The receiver operating characteristic(ROC) curves were figured, and the area under ROC curves(AUCs) were calculated to evaluate the diagnostic value of these items. The correlation between cardiac function classification of NYHA and LVESD, LVEDD, LVEF, E/Ea in CHD was analyzed. Results 1) The level of LVESD, LVEDD, E/Ea rose significantly and LVEF decreased obviously(P＜0.05) as the cardiac function classification of NYHA processed. 2) The AUCs of LVESD, LVEDD, LVEF, E/Ea were respectively0.888, 0.753, 0.123, 0.770. 3) There was a significant positive correlation between cardiac function classification of NYHA and LVESD, LVEDD, E/Ea, but a negative correlation with LVEF. Conclusion To monitor LVESD, LVEDD, LVEF, E/Ea with echocardiography can be used to assess the changes of cardiac function in CHD. |
| Key words: Coronary heart disease, Echocardiography, Doppler, Cardiac function classification of NYHA, Left ventricular function |
