Objective: To investigate the clinical value of ultrasonic bone mineral density (BMD) in early diagnosis of rickets in children, so as to provide a new method for early diagnosis of rickets in children. Methods: 160 children with rickets who were treated in our hospital from January 2015 to ~2016 in and healthy children in our hospital in December were selected as the subjects. Into the observation group (n=160) and the control group (n=100), two groups of children with ultrasonic bone mineral density detection. The correct diagnosis rate of statistical comparison of bone mineral density on early childhood rickets; secondly, the observation group and control group were compared and analyzed the value of children"s bone density; moreover, the comparison of two groups of children serum calcium, alkaline phosphatase concentration. Results: (1) compared with the gold standard in the diagnosis of rickets bone X radiography, ultrasound bone density examination method has higher diagnostic accuracy, and performance for the younger the accurate diagnosis rate is high; (2) patients in the observation group Z bone density in each age group were significantly lower than those in control group (children P<0.05), and the lower the age differences between control group and the observation group of patients with different gender, bone mineral density Z value had no significant difference (P>0.05); (3) to observe the serum calcium concentration group were lower than control group, alkaline phosphatase concentration is higher than the control group, the observation group increased with the concentration of serum calcium bone mineral density increased, the concentration of alkaline phosphatase decreased with an increase in bone density. Conclusions: through ultrasound bone density examination can early diagnosis of rickets in children, and has a high diagnostic accuracy, is a new effective method for clinical diagnosis of rickets in children, and to promote the application.