超声和MRI在胎儿心脏畸形筛查中的对比与联合应用研究
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广东省深圳市深圳华侨城医院

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2016年度深圳市科技研发资金基础研究(医疗卫生自由探索)(JCYJ20160412101452710)


The application of ultrasonic resonance MRI in the diagnosis of fetal cardiac malformation
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Shenzhen OCT Hospitai

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    摘要:

    目的 探究超声与MRI在胎儿心脏畸形筛查中的对比和联合应用价值。方法 第一阶段选取39例胎儿心脏畸形确诊病例进行MRI扫查,以超声切面图为模板创建出与其一一对应的MRI标准断层图;第二阶段以标准切面图或断层图为基础,对57例胎儿心脏畸形可疑病例进行超声诊断、MRI诊断、超声与MRI联合会诊,并将单独超声诊断、单独MRI诊断、超声与MRI联合会诊的结果与尸检或出生后随访结果进行对比分析,比较三种诊断方法的符合率。结果 通过尸检调查与随访结果,得知超声与MRI联合会诊的符合率为98.24%(误诊1例,无漏诊),明显高于单独超声诊断的符合率为85.96%(误诊5例,漏诊3例),两组数据差异具有统计学意义(χ2=4.34,P <0.05);单独MRI诊断的符合率为70.18%(误诊6例,漏诊11例),明显低于单独超声诊断的符合率,两组数据差异具有统计学意义(χ2=4.15,P <0.05)。结论 超声与MRI联合会诊的符合率明显高于单独超声诊断和单独MRI诊断的符合率,超声与MRI对比应用可知各自的优劣,联合应用可相互取长补短,并能有效提高胎儿心脏畸形筛查的检出率与准确性。

    Abstract:

    Objective to explore the application of ultrasonic combined MRI in the diagnosis of fetal cardiac malformation. Methods the first phase selection in March 2015 to March 2016 in our hospital and the shenzhen city people''s hospital and routine prenatal ultrasound diagnosis of fetal cardiac malformations of 39 cases of pregnant women by MRI scan, and sonographic views photo with templates to create one of a corresponding MRI standard fault graph; The second phase selection in March 2016 to March 2016 in our hospital and the shenzhen city people''s hospital for routine prenatal ultrasound examination of fetal cardiac malformations of 57 cases of pregnant women as the research object, on the prenatal ultrasound screening, again with MRI standard fault graph based on MRI of 57 cases of pregnant women.Final will be a single ultrasonic diagnosis, ultrasonic joint MRI diagnosis and follow-up results autopsy results or after birth detailed comparison and analysis, compare the accuracy of two methods of diagnosis. Results through the investigation and follow-up results of an autopsy that ultrasonic joint MRI diagnostic coincidence rate was 98.24% (misdiagnosis 1 case, no leak diagnosis), significantly higher than that of single ultrasound diagnosis coincidence rate was 85.96% (5 cases of misdiagnosis and missed diagnosis of 3 cases), statistically significant differences in two groups of data (chi-square = 4.34, P < 0.05). Conclusion ultrasonic combined MRI can improve the detection rate and accuracy of fetal heart abnormalities.

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周成礼.超声和MRI在胎儿心脏畸形筛查中的对比与联合应用研究[J].临床超声医学杂志,2017,19(8):535-539

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  • 收稿日期:2017-06-04
  • 最后修改日期:2017-08-08
  • 录用日期:2017-07-31
  • 在线发布日期: 2017-09-19
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