[Abstract] Objective: To evaluate the accuracy of Doppler HD-FLOW (high definition-flow) imaging in screening velamentous umbilical cord insertion of sail placenta at 11-13+6 week. Methods: a total of 2141 pregnant women who were screened in Shunde Hospital Southern Medical University; during the first trimester of pregnancy and delivered in the hospital were selected as the subjects of study (a total of 2296 fetuses). According to the different location of umbilical cord insertion during early pregnancy(11~13+6 w)were divided into three groups.: group A: HD-FLOW ultrasound examination showed that the fetal umbilical cord entrance located in membranes, were identified as sail placenta; group B: HD-FLOW ultrasound examination showed that the fetal umbilical cord and placenta in the placenta at the edge of the entrance position, it is difficult to determine the insertion point in the fetal or placental parenchyma C; HD-FLOW group: ultrasound examination showed that the fetal umbilical cord and placenta placenta essence entrance position, that the group is the normal placenta. The results were compared with the results of prenatal and postnatal. Results: early pregnancy ultrasound examination of HD-FLOW with respect to an inspection during the inspection of fetal attachment positions display a check rate and singleton, twins, three fetal display rate is higher and the difference was significant (P<0.05). At 11th-13+6 th weeks of fetal examination found that A group of 21 cases, B group of 32 cases, C group of 2243 cases. 29 cases of placenta were found in the middle pregnancy, and there were 23 cases of placenta and normal placenta in 2244 cases. After birth, 28 cases of placenta were examined, of which there were 23 cases of placenta and normal placenta in 2245 cases. The diagnostic accuracy rate of 11-13+6 weeks was 98.26% (2256/2296). Conclusion: HD-FLOW technique has a certain value in the screening of portal vein placenta in 11-13+6 weeks, and can be used to make accurate diagnosis of some placenta.