| 摘要: |
| 目的 探讨应用声触诊组织定量技术测量胰腺组织剪切波速度（SWV）评估2型糖尿病微血管并发症的可行性。方法 应用声触诊组织定量技术分别检测2型糖尿病患者有微血管并发症组（47例）、无微血管并发症组（68例）及正常对照组（115例）患者的胰腺头、体及尾部SWV值，比较三组间各部位胰腺SWV值的差异。探讨影响2型糖尿病胰体SWV值的相关因素。结果 有微血管并发症组和无微血管并发症组胰腺头、体及尾部SWV值均明显高于正常对照组，差异均有统计学意义（均P＜0.01）；有微血管并发症组胰体SWV值明显高于无微血管并发症组，差异有统计学意义（P＜0.01）。2型糖尿病患者的胰体SWV值与微血管并发症（标准化系数Beta=0.208，P=0.022）、年龄（标准化系数Beta=0.265，P=0.004）及总胆固醇（标准化系数Beta=0.223，P=0.011）呈正相关。结论 2型糖尿病患者胰体SWV值的增加与微血管并发症显著相关，胰体SWV值在评估糖尿病微血管并发症中有一定的价值。
关键词 2型糖尿病；微血管并发症；声触诊组织定量技术；剪切波速度 |
| 关键词: 2型糖尿病 微血管并发症 声触诊组织定量技术 剪切波速度 |
| DOI： |
| 投稿时间：2017-06-16修订日期：2017-10-06 |
| 基金项目:国家自然科学基金(31271235),国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| Value of pancreatic elastography by Virtual Touch Tissue Quantification for evaluation of type 2 diabetic microangiopathy |
| li xiaoping,jin chunxiang |
| (China-Japan Union Hospital of jilin University) |
| Abstract: |
| Objective To investigate the feasibility of pancreatic shear wave velocity（SWV） in evaluating type 2 diabetic microangiopathy. Methods Forty-seven cases of type 2 diabetic patients with microangiopathy and 68 cases of type 2 diabetic patients without microangiopathy were included in this study，and 115 health volunteers were taken as control group. The SWV value of pancreatic head,body and tail in those three groups were measured by VTQ technology and compared differences among three groups,respectively. Factors that were associated with the value of SWV of pancreatic body were also studied in type 2 diabetic patients. Results The SWV value of pancreatic head,body and tail increased in type 2 diabetic groups compared with those in the control（all P＜0.01）；The SWV value of pancreatic body was higher with the presence of microangiopathy in the type 2 diabetic groups（P＜0.01）. In type 2 diabetic patients，microangiopathy (Beta=0.208, P=0.022），age（Beta=0.265, P=0.004） and total cholesterol levels（Beta=0.223, P=0.011） were positively correlated with a high SWV value of pancreatic body. Conclusion The increased SWV in pancreatic body was related to the presence of microangiopathy. The SWV value of pancreatic body has some value in evaluating type 2 diabetic microangiopathy.
KEY WORDS Type 2 diabetes mellitus；Microangiopathy；Virtual Touch Tissue Quantification；Shear wave velocity |
| Key words: Type 2 diabetes mellitus Microangiopathy Virtual Touch Tissue Quantification Shear wave velocity |
