| 摘要: |
| 目的 探讨应用颈动脉瞬时波强(WI)参数评价糖尿病患者的心血管功能的临床应用价值。方法 对照组与糖尿病组各66例,糖尿病组又根据有无微血管病变分为合并微血管病变组(n=36)和未合并微血管病变亚组 (n = 30)。各组均应用WI技术检测受检者左颈总动脉获得瞬时加速度波强(W1)、瞬时减速度波强(W2)和负向波面积(NA)。比较各组参数。结果 合并微血管病变的糖尿病亚组W1 和 NA 均显著低于对照亚组1 (W1: P < 0.001, NA: P = 0.015)；未合并微血管病变的糖尿病亚组W2 值低于对照亚组2 (P = 0.039 )。结论 WI技术的各参数在早期发现糖尿病患者心血管功能异常方面发挥了一定作用。 |
| 关键词: 超声心动描记术 糖尿病 瞬时波强 |
| DOI： |
| 投稿时间：2017-07-15修订日期：2017-09-06 |
| 基金项目:陕西省科技厅社发攻关基金(2013K12-09-07),陕西省教育厅科研基金(2013JK0789),西安医学院科研基金重点项目(11ZD01)。 |
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| Carotid arterial wave intensity analysis in diabetics with microangopathy |
| DUAN Yunyan |
| () |
| Abstract: |
| Objective Wave intensity (WI) is a novel hemodynamic index that provides quantitative information about the dynamic interactions between the heart and vascular system. We sought to evaluate the working condition of the heart interacting with the arterial system in diabetic patients (DM) with WI. Methods We studied 66 diabetic patients with normal left ventricular ejection fraction and 66 healthy control subjects. The diabetic patients were divided into DM with microangiopathy subgroup (n = 36) and DM without microangiopathy subgroup (n = 30). Real time WI was recorded using ALOKA α-10 machine, and the magnitudes of the first peak (W1) and the second peak (W2) as well as the negative area (NA) of carotid artery were measured. Results The values of W1 and NA in DM with microangiopathy subgroup were much lower than those in the age-matched controls (W1: P<0.001, NA: P = 0.015), and no significant difference was found in W2. The values of W1 and NA in DM without microangiopathy subgroup did not significantly differ from the age-matched control subgroup. Conversely, the value of W2 of this subgroup was much lower than the controls (P = 0.039). Conclusion Carotid arterial WI parameters play an important role in evaluating the impaired working condition of both heart and arterial system of diabetic patients. |
| Key words: Echocardiography Diabetic mellitus Wave intensity |
