| 摘要: |
| 【摘要】
目的 研究健康人群脑供血比的年龄变化及相关影响因素。
方法 140例健康查体者，使用彩色多普勒超声测量脑血流量及心输出量，并记录测量其他相关一般指标和血流动力学参数。使用线性相关及多元回归分析进行数据处理。
结果 脑供血比以每十年1.3%的速度减少。女性脑供血比高于男性（18.68%±6.15%vs. 13.23%±4.93%, P<0.01）。经线性相关分析，BMI、血压、脉搏波传导速度、脑血管阻力与脑供血比显著相关（P<0.01）；经多元回归分析校正后，仅BMI与脑供血比独立负相关（β=-0.311，P<0.01）
结论 健康人群中，脑供血比随年龄增长而减低，且女性脑供血比一直高于男性。BMI (体质指数) 与脑供血比独立负相关。 |
| 关键词: 脑供血比 多普勒超声 性别 BMI |
| DOI： |
| 投稿时间：2017-07-18修订日期：2017-08-22 |
| 基金项目:陕西省自然基础研究项目 |
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| Ultrasonic evaluation on proportion of blood flow to the brain with aging in healthy subjects |
| lifan |
| () |
| Abstract: |
| [Abstract]
Objective To investigate the aging change of proportion of blood flow to the brain from the heart and corresponding influential factors in healthy subjects.
Methods In present study, 140 healthy subjects out of health examination population were recruited. Their cerebral blood flow and cardiac output were measured by Color Doppler Ultrasound. The related characteristics and hemodynamics were also recorded and determined. Data were analyzed by linear correlation and regression.
Results The proportion of blood flow to the brain decreased at a rate of 1.3% per decade. This proportion is higher in women than men (18.68%±6.15% vs. 13.23%±4.93%, P<0.01). The linear correlation showed that BMI, blood pressure, pulse wave velocity and cerebrovascular resistance were negatively related with this proportion (P<0.001); whereas BMI was the only independent associated factors after multiple regression (β=-0.311，P<0.01).
Conclusions In healthy population, the proportion of blood flow to the brain decreased with aging, which is higher in women and negatively associated with BMI. |
| Key words: Proportion of blood flow to the brain Doppler Ultrasound Sex BMI |
