ABSTRACT Objective We observed the remodeling of basilar artery（BA）following common carotid artery(CCA) ligation in animal model we made. Methods Twenty healthy white rabbits which bilateral CCA were ligatured. The BA of rabbits were examined before operation, at the immediate，2 days, 7 days, 30 days after operation respectively by Color-coded Doppler Ultrasonography. The shape and course of BA were observed, the diameters(D) of BA were measured, the hemodynamic parameters such as systole peak velocity(Vs), diastole velocity(Vd), mean velocity(Vm), the pulsatility index(PI) and resistance index(RI) were recorded, BA flow(Q) were computed according to the equation. Results After bilateral carotid artery ligation, the flow of basilar artery increased and reached a peak at the 2th day after operation, the shape of basilar artery twisted and became severely with time, the diameter of basilar artery widened significantly at the 30th day after operation, compared with that before operation (P < 0.01). Vs, Vd, and Vm reached a peak at the 2th day after surgery, then began to slow down gradually. Conclusions Increased BA flow results in adaptive BA remodeling following bilateral CCA ligation. Morphological changes occur rapidly following flow alteration and do not require chronic insult to affect substantial and significant structural transformation. Additionally, it appears that there exists a flow-increase threshold, when surpassed, results in significant tortuosity.