Objective: To investigate the visualization capability of ultrasonography in adult paraglottic space (PGS) and measure the depth of PGS at the planes of ventricular band and vocal cord. Methods: 240 adults were enrolled with diseases in the larynx and hypopharynx area excluded, including 120 men and 120 women, and divided into 18～44 years, 45～59 years, and ≥60 years group. The visualization capability of the PGS was evaluated at the planes of ventricular band and vocal cord, by grading criteria of “excellent”, “good”, and “poor” according to the degree of thyroid cartilage calcifications. The depth of PGS was measured in the adults with visualization capability categorized as “excellent” and “good”. Results: The visualization capability of the PGS was better in the plane of ventricular band than that of vocal cord (75.0％～98.1％ vs 38.5％～95.4％). Also that was better in female adults compared with the male (61.4%～98.1% vs 38.5%～91.2%). The visualization capability of the PGS was degraded with age increased (83.3%～98.1% vs 38.5%～91.9%). PGS was thicker in the planes of ventricular band than that of vocal cord (male adults, 2.24±0.25mm vs 1.69±0.21mm; female adults, 2.10±0.31mm vs1.61±0.26mm, both P＜0.001). Male adults, the group aged 45～59 years, and ≥60 years tend to have thicker PGS when compared with their counterparts. Conclusions: The PGS can be well visualized in most normal adults by using high-frequency sonography. At the plane of ventricular band, the female, and the young and middle-aged group have better visualization quality of PGS. Normal depth values of the PGS are obtained. PGS is thicker at the plane of ventricular band, especially in male adults and in the middle-aged and old people.