Objective To assess the clinical value of two-dimensional speckle tracking imaging(2D-STI) in detecting the left ventricular systolic and diastolic function of the patients with metabolic syndrome(MS). Methods In case group, thirty MS patients were selected and examined for common echocardiography, and 2D-STI were also used to measure the left ventricular global peak systolic longitudinal strain（GLS），global peak circumferential strain(GCS), the basal and apical rotation angle, peak twisting and untwisting speed, calculate twisting angle and untwisting rate. Another thirty healthy volunteers were enrolled as control. Results Compare to control, MS patients’ left atrial diameter, left ventricular end diastolic diameter, interventricular septal thickness, left ventricular posterior wall thickness, Left ventricular mass index and E/e ratio were lager(P<0.01), and E/A ratio was lower(P<0.01). Left ventricular ejection fraction（LVEF）had no significant difference between two groups（P>0.05）. Compare to control, MS patients’GLS was lower(P<0.01), twisting angle was larger(P<0.01), peak twisting and untwisting speed were faster(P<0.05) and untwisting rate was lower(P=0.01). GCS had no significant difference between two groups（P>0.05）.Conclution The left ventricular systolic and diastolic function of MS patients had reduced at early stage. 2D-STI technology can be detection of quantitative changes in left ventricular function in MS patients.