| 摘要: |
| 目的 探讨实时超声剪切波弹性成像在急性肌肉损伤的应用价值。方法 选用健康成年雄性新西兰大白兔20只,分为正常组和损伤组,损伤组制作成急性肌肉钝挫伤模型。应用实时超声剪切波弹性成像,获取正常肌肉及损伤后12小时、1天、3天、5天、7天、14天的杨氏模量平均值(Emean) 和最大值(Emax),并在各时间点取材进行病理学观察。结果 损伤后不同时间点的杨氏模量平均值(Emean) 和最大值(Emax)均显著高于正常组的Emean和Emax(F Emean= 10.216 ,P Emean =0.000； F Emax =11.286,P Emax=0.000),且于损伤后1天内逐渐增大,于1天后呈逐渐下降趋势。病理结果提示不同时间点炎症细胞浸润的数量不全相同(c2=46.588,P=0.000),损伤后第1天炎症细胞浸润最为显著。结论 超声剪切波弹性成像作为一种新技术,在急性肌肉损伤中能很好地观察肌肉损伤和修复的变化,可以为临床评估肌肉损伤提供可靠的依据。 |
| 关键词: 超声检查 弹性成像 肌肉损伤 炎症 |
| DOI： |
| 投稿时间：2017-09-11修订日期：2017-09-11 |
| 基金项目:广东省省级科技计划项目 |
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| The experimental study on evaluation of acute muscle injury in rabbits by ultrasonic shear wave elastography |
| Zhou Xiaohua,Qiu Shaodong |
| (Department of Ultrasound,the Second Affiliated Hospital of Guangzhou Medical University) |
| Abstract: |
| Objective To explore the application value of real-time ultrasonic shear wave elastography in acute muscle injury. Methods 20 healthy adult male New Zealand rabbits were divided into healthy group and injury group. Injury group were made into acute muscle contusion model. Real-time ultrasonic shear wave elastography was performed in each rabbit. The Young’s modulus were obtained from normal muscles and injured muscles at 12 hours, 1 days, 3 days, 5 days, 7 days, 14 days after contusion. Then the specimens were taken for pathological observation. Results The young's modulus after injury in different time average value (Emean) and maximum modulus (Emax) values were significantly higher than the normal group（F Emean= 10.216 ,P Emean =0.000; F Emax =11.286,P Emax =0.000））. The Mean values and the Max values of Young’s modulus were increase gradually in 1 days after injury, then showed a gradual decrease. Pathological findings showed that the number of infiltrating inflammatory cells was not the same at different time points （χ2=46.588，P=0.000）, and the infiltration of inflammatory cells was most significant at first days after injury. Conclusion As a new technology, Ultrasonic shear wave elastography can well observe the changes of muscle damage and the healing in acute muscle injury. So it can provide a reliable basis for the clinical assessment of muscle injury. |
| Key words: Ultrasonography Elastography Muscle injury Inflammation |
