To understand the difference between 2d and 3d speckle tracking technology for left ventricular systolic function detection and evaluation in children with kawasaki disease, and to provide theoretical experience for the clinical use of this technique. Methods During January 2014 - December 2016， in 50 cases of children with kawasaki disease in our hospital research， analysis of the use of 2 d - STE and 3 d - STE children heart was detected in different position （base）， middle section， apex of specific parameters （left ventricular end-diastolic volume and left ventricular ejection fraction， end systolic volume， longitudinal strain， ring to strain， radial strain）， coronary artery expansion with the condition of non-uniform statistical differences. Results The children were tested using 2D-STE and 3D-STE respectively， and the differences in EDV， ESV and results showed statistical significance （P< 0.05）. The difference between LVEF results was not statistically significant （P> 0.05）. The differences of LS， CS and RS were statistically significant （P < 0.05）， respectively， when 2D-STE and 3D-STE were used to detect the strain of each part of the heart muscle. In the middle segment， the difference of LS was statistically significant （P < 0.05）. The differences in the detection of the apex of the heart， LS， CS and RS were statistically significant （P < 0.05）. The difference between the test results of LS， CS and RS in different parts was statistically significant （P < 0.05）. The difference between different sites of LS， CS and RS was statistically significant （ P< 0.05）. The children were using 2D-STE and 3D-STE for cardiac exploration， and the two methods were used to detect the left coronary artery， right coronary artery （dilation and inhomogeneity）， and the differences in the test results were not statistically significant （P > 0.05）. Conclusions 3D-STE is more comprehensive and accurate than 2D-STE detection method, and it can reflect the contractile function of left ventricle in children with kawasaki disease earlier.