| 摘要: |
| 摘 要 目的 探讨超微血管成像技术（Superb Microvascular Imaging，SMI）在慢性乙型病毒性肝炎肝纤维化程度诊断中的价值。方法 应用SMI技术评估57例慢性乙型病毒性肝炎患者肝表面附近微血管的形态，根据血管形态，将SMI图像分为5级并进行血管评分，同时行肝脏活组织病理学检查，比较病理各期所对应的SMI图像分级及血管评分，并对肝纤维化程度与肝表面附近微血管的形态进行相关性分析。结果 重度纤维化组SMI评分（S3或S4，2.72±0.98）较轻中度纤维化组（S1或S2，1.63±0.87）高。SMI技术诊断轻中度、重度肝纤维化的ROC曲线下面积为0.783，最佳截断值为2.5，敏感度和特异度分别为60.0%、87.3%。肝纤维化程度与SMI图像分级间存在密切程度高的正相关关系（Gamma=0.799>0,P<0.001）。结论 SMI技术可以通过对肝表面附近微血管形态的分析，无创性的评估肝纤维化的程度。 |
| 关键词: 超微血管成像技术 肝纤维化 超声 |
| DOI： |
| 投稿时间：2017-10-30修订日期：2017-11-28 |
| 基金项目: |
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| Value of SMI for the Evalution of Hepatics Fibrosis in Chronic Hepatitis B |
| gao meijuan |
| (Department of Ultrasound,the First Affiliated Hospital of Harbin Medical University) |
| Abstract: |
| ABSTRACT Objective To explore the value of superb microvascular imaging(SMI) to the diagnosis of chronic hepatitis B. Methods We recruited 57 patients with biospy-proven chronic hepatitis B , Useing the SMI to assess the vascular pattern in the vicinity of the liver surface. SMI images were classified into five groups accoriding to the vascular pattern and SMI vascular score was performed , and these patterns were compared with the fibrosis stage. The correlation between the degree of liver fibrosis and the vascular pattern in the vicinity of the liver surface were assessed.Results The SMI score was higer in patients with advnced liver fibrosis(S3 or S4,2.72±0.98) than those with mild-to-moderate liver fibrosis (S1 or S2,1.63±0.87). When the optimal cut-off value was 2.5, the AUC for advnced liver fibrosis was 0.783, and the sensitivity and the specificity were 60.0% and 83.3%. Liver fibrosis stage and the SMI vascular pattern have a high degree of positive correlation (Gamma=0.799>0, P<0.001).
Conclution SMI appears to be a reliable tool to predict the extent of HBV liver fibrosis noninvasively by detecting the vascular pattern in the vicinity of the liver surface. |
| Key words: Superb microvascular imaging Liver fbrosis Ultrasound |
