Objective To explore the clinical value of echocardiography in the fetus of systemic lupus erythematosus pregnant women．Methods From October 2014 to October 2017,43 fetuses of systemic lupus erythematosus pregnant women in Binzhou people’ s Hospital were selected as the research object,47 fetuses of normal pregnant women were selected in the same period as the control group,the results of#$NLechocardiography between the two groups were compared。Results The difference in the Tei index of Left and right ventricle、the cardiac morphology (LVDD、 LVSD、RVDD、ＲVSD)、the Valve abnoralities、the pericardial effusion、the pulmonary hypertension and the slow heart rate between the two groups was statistically significant between the groups( P＜0.05). Conclusion The possibility of fetal heart malformations among systemic lupus erythematosus pregnant women is relatively large,as an uninvasive and convenient method for evaluating cardiac structure and function,fetal echocardiography plays an important role in the evaluation of heart tructure and function of echocardiography in the fetus of systemic lupus erythematosus pregnant women.Therefore,fetal echocardiography should be done as soon as possible for the systemic lupus erythematosus pregnant women,thereby scientific and effective management and guidance can be conducted on pregnant women,which can reduce the occurrence of fetal heart malformation in a certain extent．