| 摘要: |
| 【】 目的 应用三维斑点追踪技术(3D-STI)评价慢性肾脏病(CKD)患者的左室整体及局部收缩功能,讨论左室整体、局部应变与左室射血分数(LVEF)之间的关系。方法 选取CKD患者48例,其中EF≥55%者21例为A组,EF＜55%者27例为B组,以及健康对照者20例。均进行3D-STI检查,获得左室整体纵向应变(GSL)、整体面积应变(GSA)、整体径向应变(GPR)及各节段的纵向应变(rSL)、径向应变(rSR)、面积应变(rSA)。采用Pearson相关分析法分析CKD患者GSL、GSA、GSR与LVEF之间的相关性。 结果 ① 整体应变：健康对照组、A组、B组GSL、GSA、GSR差异均有统计学意义(p <0.01)。两两比较中,A组GSL与对照组相比减低,差异有统计学意义(p <0.01)；B组GSL、GSA、GSR相较正常对照组减低,差异有统计学意义(p <0.01)。②局部应变：三组间rSL、rSA、rSR差异均有统计学意义(p <0.05)。与对照组相比,A组基底段rSL明显减低(p <0.01),中间段、心尖段无明显减低；与对照组、A组相比,B组基底段、中间段、心尖段rSR均明显减低(p <0.05)；B组基底段、中间段、心尖段rSA明显减低(p <0.01)。 Pearson相关分析表明CKD患者GSL、GSA、GSR与左室射血分数(LVEF)均具有良好的相关性(r=-0.712、0.760、-0.810 p < 0.01)。结论 3D-STI是一种能够有效评估CKD患者左室收缩功能的方法,且整体纵向应变、局部纵向应变能较敏感地识别左室收缩功能受损。 |
| 关键词: 斑点追踪技术，三维 肾脏病，慢性 心室应变，左 |
| DOI： |
| 投稿时间：2017-12-21修订日期：2017-12-21 |
| 基金项目: |
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| Assessment of global and regional left ventricular strain by three-dimensional speckle tracking imaging in patients with chronic kidney diseaseKe Qianqian, Yang Jingzhou, Ou Yangda. Department of Ultrasound, Zhongnan Hospital of Wuhan University, Wuhan 430030, China |
| keqianqian |
| (Zhongnan Hospital of Wuhan University) |
| Abstract: |
| 【】Objective To evaluate global and regional left ventricular(LV) strain of patients with chronic kidney disease(CKD) by three-dimensional speckle tracking imaging(3D-STI) and discuss the possible association between global strain, regional strain and ejection fraction of LV. Methods The study includes 48 CKD patients, including 21 patiients with EF≥55% in group A, 27 patients with EF＜55% in group B, and 20 healthy controls. Global peak longitudinal strain(GSL),global peak area strain(GSA), global peak radial strain(GSR), regional peak longitudinal strain(rSL), regional peak area strain(rSA), regional peak radial strain(rSR) were measured by 3D-STI. Then possible association between GSL, GSA, GSR and LVEF were discussed by the Pearson correlation analysis. Results ①Global peak strain: The GSL, GSA, GSR were statistically different in the control group, patients in group A and group B(p <0.01). There were significant differences between groups(p <0.01)as following, GSL was lower in group A(p <0.01), all of GSL, GSA, GSR were lower in group B compared with control group (p <0.01). ②Regional peak strain: The rSL, rSA, rSR were statistically different in the control group, group A and group B(p <0.05).Compared with control group, rSL of basal segments were lower in group A, while there were no differences in middle and apical segments. Compared with control group and group A, rSR, rSA in group B were lower from the basal to the apical segments(p <0.05). The Pearson correlation analysis revealed GSL, GSA, GSR were strongly associated with LVEF(r=-0.712、0.760、-0.810 p < 0.01).Conclusions 3D-STI is an effective way to evaluate the systolic strain of CKD patients. The global and regional peak longitudinal strain can recognize systolic dysfunction more sensitively. |
| Key words: speckle tracking imaging, three-dimensional kidney disease, chronic ventricular strain, left |
