| 摘要: |
| 目的：探索声脉冲辐射力弹性成像在小儿肾小球疾病中的应用价值。方法：采用声脉冲辐射力弹性成像（ARFI）技术，对228例病例组及200例健康儿童分别进行弹性成像检测及血清学检测，其中，病例组均为经肾脏穿刺活检并经病理结果证实为肾小球疾病的患儿，将测得的剪切波速度（SWV）值与血清学指标及肾脏损害程度进行统计学分析。
结果：肾小球疾病组与正常肾脏组的肾脏SWV值差异无统计学意义（P>0.05）；肾小球疾病组肾脏不同损害程度的肾脏SWV值差异无统计学意义（P>0.05）；肾小球疾病组不同血清学检测结果间肾脏SWV值差异无统计学意义（P>0.05）。
结论：ARFI技术在早期儿童肾小球疾病的评估中有一定局限性，ARFI技术在慢性肾脏疾病终末期中的应用前景尚需进一步探索。 |
| 关键词: 声脉冲辐射力弹性成像，儿童，肾小球疾病，肾脏损害 |
| DOI： |
| 投稿时间：2018-01-04修订日期：2018-01-04 |
| 基金项目: |
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| EVALUATION OF GLOMERULAR DISEASE RENAL DAMAGE IN CHILDREN BY ACOUSTIC RADIATION FORCE IMPULSE IMAGING |
| Xu Juan |
| () |
| Abstract: |
| Objective: To explore the value of ARFI in children with Glomerular disease .Methods: Totally 228 cases diagnosed with glomerular disease who accepted the renal biopsy and confirmed by pathological and 200 healthy children underwent acoustic radiation force impulse imaging (ARFI) and serological tests respectively, shear wave velocity (SWV) values were compared among different serological indexes and degree of renal damage ; to explore the clinical value of SWV value evaluate glomerular disease renal damage in children. Results: SWV of glomerular disease group and normal kidney had no significant differences (P > 0.05); there were no significant differences of SWV among group of renal glomerular disease renal damage and different serological test results ( P > 0.05).Conclusion: ARFI technology have some limitations in the assessment of the early glomerular disease in children, and application prospect of ARFI in the terminal stage of chronic kidney disease needs further exploration. |
| Key words: Acoustic Radiation Force Impulse, Children, glomerular diseases,renal damage |
