Cardiac myxoma is the most common primary cardiac tumor in the routine clinic service. At present, the cognitive level of cardiac myxoma still needs to be improved, and the further relevant basic, imaging and clinical researches are urgently needed. In clinical practice, a systematic method for the systemic diagnosis of cardiac myxoma based on basic, imaging and clinical researches should be established and should be actively applied in clinical practice to ensure the accuracy of clinical diagnosis and the reliability of prognosis prediction, and to guide a more precise formulation for the clinical treatment planning.