Preoperative neoadjuvant chemotherapy (NAC), as one of the important methods of comprehensive treatment of breast cancer, can improve the prognosis of patients with locally advanced breast cancer and their quality of life. Contrast-enhanced ultrasound and elastography can not only evaluate the tumor size, but also the changes in tumor function and internal components(microvessels, hardness, etc), which has potential value in the evaluation of neoadjuvant chemotherapy for breast cancer. The relevant studies of contrast-enhanced ultrasound and elastography in the evaluation of neoadjuvant chemotherapy for breast cancer is reviewed in this paper.