| 摘要: |
| 目的 分析肝局灶性结节状增生（FNH）在超声造影中的增强模式及特征性表现，以探讨超声造影对FNH定性诊断的临床价值。方法 收集经病理证实且术前均行超声造影检查的FNH患者的病例资料，对其临床资料、普通超声以及超声造影的声像图进行回顾性分析。结果 收集到FNH患者112例，其年龄以18～50岁居多，其男女比为1.11:1。普通二维超声以低回声为主，彩色多普勒超声有31例（31/112，27.68%）显示出轮辐状血流信号。超声造影三期（动脉期、门脉期和延迟期）的增强模式以“高-高-高”（49/112，43.75%）和“高-等-等”（44/112，39.29%）为主；其特征性征象有离心性增强(62/112，55.36%)、轮辐状动脉(59/112，52.68%)、中央星芒状瘢痕(52/112，46.43%)；其中轮辐状动脉、中央瘢痕多见于大病灶组（≥3cm）（P<0.01）；而离心性增强则是小病灶组（<3cm）中最主要的表现。普通超声的诊断符合率为32.14%，而超声造影的诊断符合率达89.28%。结论 超声造影能明显提高FNH的无创定性诊断符合率。 |
| 关键词: 肝 局灶性结节状增生 超声检查 造影剂 |
| DOI： |
| 投稿时间：2018-08-09修订日期：2018-10-22 |
| 基金项目:国家国际科技合作专项(2015DFA30920)；重庆市国际科技合作专项(cstc2014gjhz110004)；重庆市社会民生科技创新专项项目（cstc2016shmszx130080） |
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| The clinical diagnosis value of contrast-enhanced ultrasound for hepatic focal nodular hyperplasia |
| TAN Ying,guoyanli |
| (Department of Ultrasound, Southwest Hospital, Third Military Medical University (Army Medical University)) |
| Abstract: |
| ABSTRACT Objective To analyze the enhancement pattern and characteristic features of hepatic focal nodular hyperplasia (FNH) in contrast-enhanced ultrasound, and to evaluate the qualitative diagnosis value of contrast-enhanced ultrasound for FNH. Methods Data of patients with FNH confirmed by pathology and preoperative contrast-enhanced ultrasound were collected. Their clinical data, conventional ultrasound images and contrast-enhanced ultrasound images were retrospectively analyzed. Results A total of 112 cases with FNH were enrolled, the majority of which were aged from 18 to 50 years, and the ratio of male to female was 1.11:1. The conventional ultrasound was mainly characterized by low echoes, and radiant blood flow signal was visualized in 31 cases (31/112, 27.68%). The enhancement patterns of the contrast-enhanced ultrasound three phases (arterial, portal venous, and delayed phase) mainly presented as hyper-hyper-hyper-enhancement (49/112, 43.75%) and hyper-iso-iso enhancement (44/112, 39.29%). The characteristic features included centrifugal enhancement (62/112, 55.36%), wheel-shaped radiant artery (59/112, 52.68%), and central stellate scar (52/112, 46.43%). Among them, the wheel-shaped artery and central stellate scar was commonly observed in the large lesion size group (≥ 3 cm) (P<0.01), while the centrifugal enhancement was more common in the small lesion size group (< 3 cm). The diagnosis coincidence rate of conventional ultrasound was 32.14%, and the rate of contrast-enhanced ultrasonography was 89.28%. Conclusions The contrast-enhanced ultrasonography can significantly improve the noninvasive diagnostic accuracy of FNH. |
| Key words: Liver Focal nodular hyperplasia Ultrasonography Contrast agent |
