| 摘要: |
| 目的：探讨晚孕期胎儿静脉导管频谱参数在妊娠期糖尿病(GDM)中预测妊娠结局的应用价值。方法：选择晚孕期249例妊娠期糖尿病孕妇作为研究对象,应用超声检测胎儿静脉导管(DV)频谱参数包括S、D、a、v、TAmax、S/a、PI、PLI及PVIV,随访至妊娠结束,比较两组不同妊娠结局组之间的参数,分析其与妊娠结局的相关性。结果：1、不良妊娠结局组胎儿DV频谱参数S、v、D、a、TAmax测值均小于正常妊娠结局组,而S/a、PI、PLI及PVIV测值均大于正常妊娠结局组；其中仅S/a、PLI两组间比较差别有统计学意义(P＜0.05)；2、以S/a为1.84预测胎儿妊娠结局,ROC曲线下面积为0.614,灵敏度及特异度分别为54.05%、71.70%。以PLI为0.45预测胎儿妊娠结局,ROC曲线下面积为0.616,灵敏度及特异度分别为54.05%、70.75%。结论：应用超声监测晚孕期GDM胎儿静脉导管的频谱参数,可为临床预测胎儿妊娠情况提供依据；S/a、PLI均可以作为预测晚孕期GDM胎儿妊娠结局的指标。 |
| 关键词: 超声,妊娠期糖尿病,静脉导管,妊娠结局 |
| DOI： |
| 投稿时间：2018-09-20修订日期：2019-06-04 |
| 基金项目:上海交通大学多学科交叉项目培育青年基金(YG2015QN32)，国家自然科学青年基金项目(81501256) |
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| Study of fetal ductus venosus doppler parameter with gestational diabetes mellitus predict of pregnancy outcomes during later gestation |
| caoyunyun |
| () |
| Abstract: |
| Objective To investigate the Doppler parameter of fetal ductus venosus (DV) in predicting pregnancy outcomes during later gestation of gestational diabetes mellitus (GDM). Methods About 249 cases GDM women were in research group during later gestation. And the ventricular systole (S), ventricular diastole (D),ventricular end-systole (v),atrium systole (a), time maximum velocity (TAmax) , S/a ratio, pulsatility index(PI), preload index (PLI) and peak velocity index vein(PVIV) of DV Doppler parameters were detected by ultrasound. Those fetus were followed up to the end of the outcomes. Different pregnancy outcomes of parameters were compared, correlation of parameters and pregnancy outcomes were analyzed. Results In group of adverse pregnancy outcomes ,the the S, v, D, a, Tmax parameters of ductus venosus were less than normal pregnant women, but the S/a, PI, PLI and PVIV were more than common pregnancy outcomes group. But only S/a and PLI were with statistical significance in two groups(P＜0.05). If the predicted value of S/a is 1.84, the sensitivity and specificity values 54.05% and 71.70%. And the area under ROC curve: 0.614; And if we set the predicted value of PLI is 0.45, the sensitivity and specificity values 54.05% and 70.75%. Area under the ROC curve: 0.616. Conclusions Monitoring the fetal ductus venosus blood flow spectrum of GDM in later pregnancy by applying ultrasonic, which could provide the basis for predicting the pregnancy outcomes ; The parameters of S/a and PLI all could predict pregnancy outcomes, and PVIV had a higher predicted value. |
| Key words: Sonography Gestational diabetes mellitus Ductus venosus Pregnancy outcomes |
