| 摘要: |
| 【摘要】目的 探讨运用组织多普勒成像评价多囊卵巢综合征（PCOS）患者的左室舒张功能的价值。方法 随机对因不孕或月经不调来我院检查的体重正常或过低（A组）、超重或肥胖（B组）的PCOS患者进行常规超声心动图检查，并做好二尖瓣口舒张早期的E峰峰值速度（PEA)、二尖瓣舒张早期最大血流速度（E）与舒张晚期最大血流速度（A）的比值（E/A）、组织多普勒二尖瓣环左侧壁附着处心肌舒张早期运动峰值速度(Em)、舒张晚期运动峰值速度(Am)、Em/Am值、E/Em值等数据记录和图像采集。两组患者均空腹12小时后于清晨抽取静脉血，采用全自动生化仪测定血脂、血糖水平，采用放射免疫法检测血清胰岛素水平。结果 B组腰臀比 (WHＲ)、胰岛素抵抗指数 (HOMA-IR) 高于A组，高密度脂蛋白胆固醇 (HDL-C)低于A组，差异均有统计学意义(P＜0. 05); 两组胆固醇 (TC)、甘油三酯 (TG)、低密度脂蛋白胆固醇 (LDL-C)水平相比较，差异无统计学意义(P＞0. 05) 。A组Em、Em/Am高于B组，E/Em值小于B组，差异均有统计学意义(P＜0. 05) ; 两组其余心脏指数比较，差异均无统计学意义(P＞0. 05)。结论 肥胖合并胰岛素抵抗（IR）PCOS患者左心室舒张功能显著降低，组织多普勒评价左室舒张功能优越于传统的二尖瓣血流评价方式。 |
| 关键词: 组织多普勒 多囊卵巢综合症 心脏 舒张功能 |
| DOI： |
| 投稿时间：2018-10-23修订日期：2019-06-05 |
| 基金项目:深圳市龙岗区科技创新局立项课题 |
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| Evaluation of left ventricular diastolic function in polycystic ovary syndrome by tissue Doppler |
| Guo JinQiang |
| () |
| Abstract: |
| [Abstract] Objective To evaluate left ventricular diastolic function in patients with polycystic ovary syndrome by tissue Doppler imaging.Methods Routine echocardiographic examination of patients with polycystic ovarian syndrome (PCOS) with normal or low weight (group a), overweight or obesity (group B) due to infertility or irregular menstruation.And Record the data recording and image acquisition such as Peak e velocity in early diastole of two cusps(E), Ratio of maximum blood flow velocity (E) at the early stage of mitral valve diastole to maximum blood flow velocity (A) at late diastole (E/A), Early peak velocity of myocardial diastole in the left wall of tissue Doppler mitral annulus(Em), Late diastolic peak velocity(Am) etc. Both groups received venous blood in the early morning after 12 hours of fasting, Determination of blood lipid and blood glucose level by automatic biochemical instrument,Detection of serum insulin level by radioimmunoassay.Results Group B of Waist-to-hip ratio(WHR) and Insulin resistance index (HOMA-IR) is higher than group A. High density lipoprotein cholesterol(HDL-C)is Lower than group A. The difference is statistically significant(P<0.05). The difference of Cholesterol(TC), Triglyceride(TG) and Low density lipoprotein cholesterol (LDL-C) is not statistically significant(P＞0. 05). Group B of Em,Em/Am is higher than group A. E/Em is Lower than group A. The difference is statistically significant(P<0.05). The difference of Residual cardiac index is not statistically significant(P＞0. 05). Conclusion Left ventricular diastolic function decreased significantly in PCOS obese with insulin resistance (IR) . Evaluation of left ventricular diastolic function by tissue Doppler imaging is superior to the traditional method of evaluation of blood flow in bicuspid valve. |
| Key words: Tissue Doppler imaging polycystic ovarian syndrome heart diastolic function |
