Objective：By measuring the carotid pulse wave velocity (PWV), the effect of hyperuricemia on carotid vascular elasticity was examined, which in turn indicated the degree of carotid atherosclerosis.Methods：50 patients with hyperuricemia without hypertension, diabetes,hyperlipidemia and smoking history who were admitted to our hospital from January 2017 to September 2018 were selected as experimental group (high uric acid group). At the same time, 50 patients with non-hyperuric acid without hypertension, diabetes,hyperlipidemia and smoking history were selected as the control group (non-hyperuric acid group). Record their age separately. The systolic and diastolic PWV values of bilateral common carotid arteries were measured and compared.Results: There was no significant difference in age between the hyperuricemia group and the non-hyperuric acid group. The systolic and diastolic PWV levels of the bilateral common carotid arteries in the hyperuric acid group were significantly higher than those in the non-hyperuric acid group (P<0.05).Conclusion: Hyperuricemia can affect carotid vascular elasticity.Detection of PWV has important clinical diagnostic value for assessing carotid vascular elasticity in hyperuricemia, so that the degree of carotid atherosclerosis can be assessed.