| 摘要: |
| 【】目的 本研究采用二维斑点追踪显像技术(2D-STI)评价临床情况稳定的“健康”心脏移植患者左室收缩功能,探讨“健康” 移植心脏与正常心脏左室应变参数之间的差异,为2D-STI技术监测移植术后排异反应提供参考。方法 选取在2017-2018年在我院行心脏移植手术后长期临床随访未发现明显排异反应的患者50例作为心脏移植组(A组),30例健康志愿者作为对照组(B组),进行二维超声心动图检查,用EchoPAC软件分析心脏移植患者左室心肌内膜、心肌外膜、整体纵向应变(EndoGLS、EpiGLS、GLS)、环向应变(EndoGCS、EpiGCS、GCS)及左室整体径向应变(GRS)；结果 与正常对照组相比,心脏移植患者纵向应变参数GLS、endoGLS、epiGLS,环向应变参数endoGCS、GCS、epiGCS及径向应变参数GRS均减低(P<0.001),差异统计学意义。结论 “健康”心脏移植患者左室收缩功能与正常人相比仍然存在差异,探索更适合心脏移植患者的左室应变参数参考值范围可为2D-STI技术监测术后排异反应奠定基础。 |
| 关键词: 超声心动描记术 心脏移植 二维斑点追踪显像 左心室功能 |
| DOI： |
| 投稿时间：2019-01-19修订日期：2019-01-19 |
| 基金项目:中央高校基本科研业务费专项资金科研项目（2042017kf0165） |
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| Evaluation of left ventricular systolic function in patients with non-rejective heart transplantation by two-dimensional speckle tracking stratified strain technique |
| caidi |
| (Wuhan University Renmin Hospital) |
| Abstract: |
| 【】Objective To evaluate left ventricular (LV)systolic function in clinically stable heart transplantation patients by two-dimensional speckle tracking imaging (2D-STI) to explore the difference of left ventricular strain parameters between "healthy" transplanted heart and normal heart,providing a reference for monitoring rejection after transplantation by 2D-STE . Methods A total of 50 patients with no significant rejection after long-term clinical follow-up in our hospital were enrolled as a heart transplantation group (group A) and 30 healthy volunteers as a control group (group B). Two-dimensional echocardiography was performed. The strain parameters by EchoPAC analysis software included global longitudinal strain (GLS), GLS of endocardial and epicardial layers (endoGLS and epiGLS) and global circumferential strain (GCS), GCS of endocardial and epicardial layers(endoGCS and epiGCS), global radial strain (GRS).Results Compared with the normal control group, longitudinal strain parameters GLS, endoGLS, epiGLS, circumferential strain parameters endoGCS, GCS, epiGCS and radial strain parameters GRS were all decreased (P<0.001), and the difference was statistically significant.Conclusions Left ventricular systolic function in "healthy" heart transplant patients is still different from normal people. Exploring the range of left ventricular strain parameters that are more suitable for heart transplant patients can lay a foundation for 2D-STI technology to monitor postoperative rejection. |
| Key words: Echocardiography Heart transplantation Two-dimensional speckle tracking imaging Left ventricular |
