Objective To explore the correlation between the quantitative analysis of ultrasound imaging and the diagnosis of hormone receptor expression in breast cancer patients and its clinical application value.Methods The preoperative ultrasound features and postoperative pathological immunohistochemistry results of 125 patients with breast cancer were retrospectively analyzed. According to the expression of ER, PR and HER-2, patients were divided into two groups: hormone receptor positive group (ER+, PR+, HER-2-) and hormone receptor negative group (ER-, PR-, HER-2-). . Retrospectively analyze and evaluate the characteristics of ultrasound images of breast cancer masses, select the characteristic parameters with strong hormone receptors based on the dynamic contour model of phase information, and study the research data by using support vector machine classifier and radial basis kernel function. analysis.Results The correlation between the characteristic parameters of ultrasound quantitative group and the expression of hormone receptors showed that the lesion size, margin, internal echo, posterior echo and calcification were statistically significant (P<0.05). Conclusion Ultrasound imaging Quantitative Analysis can reduce the subjectivity of traditional ultrasound imaging evaluation, and has certain value for breast cancer hormone receptor expression and biological behavior prediction.