Kimura’s disease is a rare, chronic inflammatory disease of unknown origin. It occurs mainly in young and middle-aged Asian males, especially the Chinese and Japanese. The disorder commonly involves the head and neck region, and its histopathological features are vascular proliferation and lymphoid infiltrate rich in eosinophils (Eosinophilic hyperplastic lymphogranuloma, EHLG). We present a case of Kimura’s disease which occurred much widely in the head and neck region, including bilateral cheek, parotid, submandibular glands and cervical lymph nodes, that was entirely noted only in one patient. Here, we describe the clinical presentations and imaging characteristics(US and MRI), discuss the diagnostic difficulties and its clinical treatments.