Objective: Analysis of two-dimensional and color Doppler echocardiography of coronary anastomotic leakage and pseudoaneurysm after Bentall's operation, and to evaluate the diagnostic value of echocardiography. Methods Sixteen patients were diagnosed with coronary anastomotic leakage and pseudoaneurysm after Bentall surgery in our hospital were enrolled, and their two-dimensional and color Doppler echocardiography findings were analyzed and summarized. The results of echocardiographic diagnosis and aortic angiography were compared. Results Two-dimensional echocardiography can detect the pulsating anechoic zone around the artificial blood vessels of 16 patients, and color Doppler can show abnormal blood flow signals at the anastomotic stoma of the coronary artery. There were 9 patients occurred in the left anastomosis and 7 patients occurred in the right side among them. All the ultrasound results were coincident with aortic angiography results. Conclusion Echocardiography can detect Bentall 's postoperative coronary anastomotic leakage and concurrent pseudoaneurysm in a timely, accurate and non-invasive manner, which can be used as the first choice for clinical follow-up examination.